Enprofylline


Enprofylline
Enprofylline
Systematic (IUPAC) name
3-propyl-7H-purine-2,6-dione
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 41078-02-8 YesY
ATC code  ?
PubChem CID 1676
DrugBank DB00824
ChemSpider 1613 YesY
UNII DT7DT5E518 N
ChEBI CHEBI:126237 N
ChEMBL CHEMBL279898 N
Chemical data
Formula C8H10N4O2 
Mol. mass 194.190 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Enprofylline (3-Propylxanthine) is a xanthine derivative used in the treatment of asthma, which acts as a bronchodilator. It acts primarily as a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine receptor antagonist.[1][2]


References

  1. ^ Lunell E, Svedmyr N, Andersson KE, Persson CG (1982). "Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease". European Journal of Clinical Pharmacology 22 (5): 395–402. PMID 6288396. 
  2. ^ Laursen LC (December 1987). "Anti asthmatic effects and pharmacokinetics of enprofylline--a new xanthine derivate". Danish Medical Bulletin 34 (6): 289–97. PMID 3325233. 

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