Fastigial nucleus

Brain: Fastigial nucleus
Gray707.png
Sagittal section through right cerebellar hemisphere. The right olive has also been cut sagitally. (Fastigial nucleus visible but not labeled.)
Latin nucleus fastigii
Gray's subject #187 796
Part of cerebellum
NeuroNames hier-687
NeuroLex ID birnlex_1146

The fastigial nucleus or nucleus fastigii refers specifically to the concentration of gray matter nearest to the middle line at the anterior end of the superior vermis, and immediately over the roof of the fourth ventricle, from which it is separated by a thin layer of white matter.[1] It is smaller than the nucleus dentatus, but somewhat larger than the nucleus emboliformis and nucleus globosus, the other two independent centers of gray matter in the cerebellum.

The fastigial nucleus is the smallest in size, with the dentate being the largest and the interposed being intermediate in size.

Relations and function

The fastigial nucleus receives its afferent input from the vermis. Most of its efferent connections travel via the inferior cerebellar peduncle to the vestibular nuclei, which is located at the junction of the pons and the medulla oblongata.

The fastigial nucleus deals with antigravity muscle groups and other synergies involved with standing and walking.[2]

The fastigial nucleus contains excitatory axons which project beyond the cerebellum, unlike the Purkinje cells that convey the purely-inhibitory output of the cerebellar cortex. The likely neurotransmitters of the excitatory fastigial nucleus axons are glutamate and aspartate.

The Purkinje cells of the cerbellar cortex project into the deep cerebellar nuclei and inhibit the excitatory output system.

References

  1. ^ John K. Harting, Ph.D. (1997). "The Global Cerebellum '97". University of Wisconsin Medical School. http://www.neuroanatomy.wisc.edu/cere/text/P5/S/C50.htm. Retrieved 2007-06-28. 
  2. ^ James D. Geyer, Janice M. Keating, Daniel C. Potts (1998). Neurology for the Boards. Philadelphia: Lippincott-Raven. p. 9. 

External links

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained within it may be outdated.


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • fastigial nucleus — n a nucleus lying near the midline in the roof of the fourth ventricle of the brain called also roof nucleus * * * n. fastigii …   Medical dictionary

  • Nucleus (neuroanatomy) — In neuroanatomy, a nucleus is a brain structure consisting of a relatively compact cluster of neurons. It is one of the two most common forms of nerve cell organization, the other being layered structures such as the cerebral cortex or cerebellar …   Wikipedia

  • fastigial — fas·tig·ial fa stij (ē )əl adj of or associated with the fastigium of the fourth ventricle of the brain * * * fas·tig·i·al (fas tijґe əl) of or pertaining to the fastigium or to the cerebellar fastigial nucleus …   Medical dictionary

  • nucleus fastigii — [TA] fastigial nucleus: the most medial of the cerebellar nuclei, near the midline in the roof of the fourth ventricle; it projects to the pons and medulla oblongata, chiefly to the vestibular nuclei. It is the term preferred in official… …   Medical dictionary

  • Nucleus — 1) In cell biology, the structure that houses the chromosomes. 2) In neuroanatomy, a group of nerve cells. * * * 1. In cytology, typically a rounded or oval mass of protoplasm within the cytoplasm of a plant or animal cell; it is surrounded by a… …   Medical dictionary

  • Dentate nucleus — This article is about the dentate nucleus. For other dentate, see Dentate. Brain: Dentate nucleus Sagittal section through right cerebellar hemisphere. The right olive has also been cut sagitally. (Dentate nucleus labeled at top.) Latin nucleus… …   Wikipedia

  • Globose nucleus — Brain: Globose nucleus Sagittal section through right cerebellar hemisphere. The right olive has also been cut sagitally. (Emboliform nucleus not labeled, but region is visible.) ) Latin nucleus globosus Gray s …   Wikipedia

  • Subthalamic nucleus — Brain: Subthalamic nucleus Coronal slices of human brain showing the basal ganglia, subthalamic nucleus (STN) and substantia nigra (SN) …   Wikipedia

  • Cuneate nucleus — Brain: Cuneate nucleus Dissection of brain stem. Dorsal view. (Label for nucleus cuneatus is on left, third from the bottom.) …   Wikipedia

  • Red nucleus — Not to be confused with Red blood cell#Nucleus. Brain: Red nucleus Transverse section through the midbrain showing the location of the red nuclei. The superior colliculi are at the top of image and the cerebral peduncles at the bottom of image –… …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.