Drug-induced autoimmune hemolytic anemia

Drug-induced autoimmune hemolytic anemia
Classification and external resources
ICD-10 D59.0
ICD-9 283

Drug-induced autoimmune hemolytic anemia is a form of hemolytic anemia.

Penicillin in high doses can induce immune mediated hemolysis[1] via the hapten mechanism in which antibodies are targeted against the combination of penicillin in association with red blood cells. Complement is activated by the attached antibody leading to the removal of red blood cells by the spleen.

The drug itself can be targeted by the immune system, e.g. by IgE in a Type I hypersensitivity reaction to penicillin, rarely leading to anaphylaxis.

See also

  • List of circulatory system conditions
  • List of hematologic conditions

References

  1. ^ Stroncek D, Procter JL, Johnson J (May 2000). "Drug-induced hemolysis: cefotetan-dependent hemolytic anemia mimicking an acute intravascular immune transfusion reaction". Am. J. Hematol. 64 (1): 67–70. doi:10.1002/(SICI)1096-8652(200005)64:1<67::AID-AJH12>3.0.CO;2-Z. PMID 10815791. 

Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Drug-induced nonautoimmune hemolytic anemia — Classification and external resources ICD 10 D59.2 ICD 9 283 Drug induced …   Wikipedia

  • Warm autoimmune hemolytic anemia — DiseaseDisorder infobox Name = Warm antibody autoimmune hemolytic anemia ICD10 = ICD10|D|59|1|d|55 ICD9 = ICD9|283.0 Caption = ICDO = OMIM = DiseasesDB = 29723 MedlinePlus = eMedicineSubj = eMedicineTopic = Warm Antibody Autoimmune Hemolytic… …   Wikipedia

  • Hemolytic anemia — ICD9|283, ICD9|773 ICDO = OMIM = MedlinePlus = 000571 eMedicineSubj = med eMedicineTopic = 979 MeshID = D000743Hemolytic anemia is anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs) either in the blood vessels… …   Wikipedia

  • Congenital hemolytic anemia — Classification and external resources ICD 10 D55 D58 ICD 9 …   Wikipedia

  • Microangiopathic hemolytic anemia — MAHA redirects here. For the governing body formerly known as Manitoba Amateur Hockey Association, see Hockey Manitoba. Microangiopathic hemolytic anemia Classification and external resources ICD 10 D59.4 ICD 9 …   Wikipedia

  • immune hemolytic anemia — immunohemolytic anemia an acquired hemolytic anemia in which hemolysis takes place in response to isoantibodies or autoantibodies produced on exposure to drugs, toxins, or other antigens. See also autoimmune hemolytic a., drug induced immune… …   Medical dictionary

  • Drug eruption — Classification and external resources Examples of drug eruptions. (A) Bullous dermatitis caused by sulfathiazole (B) Fixed drug eruption caused by phenolphtalein (C) Bullous erythema multiforme (D) Diffuse photosensitivity reaction …   Wikipedia

  • Autoimmune disease — Autoimmune diseases Classification and external resources ICD 10 D84.9, M35.9 ICD 9 279.4 …   Wikipedia

  • Anemia — For other uses, see Anemia (disambiguation). Anemia Classification and external resources ICD 10 D50 D64 ICD 9 …   Wikipedia

  • Pernicious anemia — Classification and external resources ICD 10 D51.0 ICD 9 281.0 …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.