Benign fibrous histiocytoma
Dermatofibroma Classification and external resources ICD-10 D23 (ILDS D23.L62) ICD-9 216.9 ICD-O: M8830/0 DiseasesDB 29384 eMedicine derm/96 MeSH D018219
Benign fibrous histiocytomas (also known as "Dermal dendrocytoma," "Dermatofibroma," "Fibrous dermatofibroma," "Fibrous histiocytoma":668, "Fibroma simplex", "Nodular subepidermal fibrosis", and "Sclerosing hemangioma") are benign skin growths.
Dermatofibromas are hard papules (rounded bumps) that may appear in a variety of colors, usually brownish to tan. Although typical dermatofibromas cause little or no discomfort, itching and tenderness can occur. Some physicians and researchers believe dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks. They are composed of disordered collagen laid down by fibroblasts. In rare cases, basal cell carcinoma may develop in a dermatofibroma.
They are usually found on the leg.
Dermatofibromas occur most often in women; the male to female ratio is about 1:4.
Neoplasm CD34 Stromelysin-3 Factor XIIIa Dermatofibroma + + + Dermatofibrosarcoma protuberans + - -
- ^ a b c d e Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ a b c Freedberg, et. al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
- ^ "benign fibrous histiocytoma" at Dorland's Medical Dictionary
- ^ a b Pierson, Joseph C.; Diane M Pierson. "Dermatofibroma". eMedicine. WebMD. http://emedicine.medscape.com/article/1056742-overview. Retrieved 2009-06-13.
- ^ "dermatofibroma" at Dorland's Medical Dictionary
- ^ Hanly AJ, Jordà M, Elgart GW, Badiavas E, Nassiri M, Nadji M (June 2006). "High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors". Archives of pathology & laboratory medicine 130 (6): 831–4. PMID 16740036. http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=130&page=831.
- ^ PMID: 17596171
- ^ http://emedicine.medscape.com/article/1056742-overview
Diseases of the skin and appendages by morphology GrowthsPigmentedDermal and
PurpuraMacularthrombocytopenic purpura · actinic purpuraPapularIndurated
Connective/soft tissue tumors and sarcomas (ICD-O 8800–9059) (C45–C49/D17–D21, 171/214–215) Not otherwise specified (8800–8809) Connective tissue neoplasmFibromatous (8810–8839)Fibroma/fibromatosis: Aggressive infantile fibromatosis · Aponeurotic fibroma · Collagenous fibroma · Diffuse infantile fibromatosis · Familial myxovascular fibromas · Fibroma of tendon sheath · Fibromatosis colli · Infantile digital fibromatosis · Juvenile hyaline fibromatosis · Plantar fibromatosis · Pleomorphic fibroma · Oral submucous fibrosisHistiocytoma/histiocytic sarcoma: Benign fibrous histiocytoma · Malignant fibrous histiocytoma · Atypical fibroxanthomaSolitary fibrous tumorMyxomatous (8840–8849)Fibroepithelial (9000–9039)Synovial-like (9040–9049) Lipomatous (8850–8889) Myomatous (8890–8929)skeletal muscle: Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma (Sarcoma botryoides) · Alveolar rhabdomyosarcoma Complex mixed and stromal (8930–8999) Mesothelial (9050–9059)see also Template:Connective tissue Tumors: Skin neoplasm, dermis (C44/D23, 173/216) Dermis Subcutaneous
vascularsee Template:Soft tissue tumors and sarcomas, Template:Vascular tumors, Template:Myeloid malignancy (for mastocytosis)Otherurogenital: Hirsuties papillaris genitalisneuro: Solitary neurofibroma · Cutaneous meningioma · Ganglioneuroma · Schwannoma · Palisaded encapsulated neuroma · Infantile neuroblastoma · Neuroma cutisnevus: Nevus anemicus · Nevus flammeus · Nevus flammeus nuchae · Nevus lipomatosus superficialis · Nevus oligemicus · Connective tissue nevus · Midline nevus flammeus · Porokeratotic eccrine ostial and dermal duct nevushistiocytoma: Malignant fibrous histiocytoma · Plexiform fibrohistiocytic tumor · Progressive nodular histiocytoma
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