Demexiptiline

Demexiptiline
Systematic (IUPAC) name
5H-dibenzo(a,d)cyclohepten-5-one O-(2-(methylamino)ethyl)oxime
Clinical data
Pregnancy cat.  ?
Legal status Prescription only
Routes Oral
Identifiers
CAS number 18059-99-9
ATC code None
PubChem CID 28876
ChemSpider 26858
UNII EYX738UZ5P YesY
Chemical data
Formula C18H18N2O
Mol. mass 278.35 g/mol
SMILES eMolecules & PubChem

Demexiptiline (Deparon, Tinoran) is a tricyclic antidepressant (TCA) used in France for the treatment of depression.[1][2] It acts primarily as a norepinephrine reuptake inhibitor similarly to desipramine.[3]

See also

References

  1. ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 301. ISBN 3-88763-075-0. http://books.google.com/books?id=5GpcTQD_L2oC&lpg=PA1267&dq=demexiptiline&as_brr=3&pg=PA301#v=onepage&q=&f=false. 
  2. ^ David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. p. 583. ISBN 0-412-46630-9. http://books.google.com/books?id=DeX7jgInYFMC&lpg=RA1-PA583&dq=demexiptiline&as_brr=3&pg=RA1-PA583#v=onepage&q=&f=false. 
  3. ^ Teste JF, Pelsy-Johann I, Decelle T, Boulu RG (1993). "Anti-immobility activity of different antidepressant drugs using the tail suspension test in normal or reserpinized mice". Fundamental & Clinical Pharmacology 7 (5): 219–26. PMID 8370568. 

Further reading

  • Martin A, Masson JM, Jusseaume P, Beloncle M, Voisinet C (November 1981). "[Demexiptiline in the treatment of melancholic states (reflections after 3 years of use)]" (in French). Annales Médico-psychologiques 139 (9): 1023–35.