CYLD (gene)


CYLD (gene)
Cylindromatosis (turban tumor syndrome)

PDB rendering based on 1ixd.
Identifiers
Symbols CYLD; CDMT; CYLD1; CYLDI; EAC; FLJ20180; FLJ31664; FLJ78684; KIAA0849; MFT; MFT1; SBS; TEM; USPL2
External IDs OMIM605018 MGI1921506 HomoloGene9069 GeneCards: CYLD Gene
EC number 3.4.19.12
RNA expression pattern
PBB GE CYLD 214272 at tn.png
PBB GE CYLD 221903 s at tn.png
PBB GE CYLD 221905 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1540 74256
Ensembl ENSG00000083799 ENSMUSG00000036712
UniProt Q9NQC7 n/a
RefSeq (mRNA) NM_001042355.1 NM_173369
RefSeq (protein) NP_001035814.1 NP_775545
Location (UCSC) Chr 16:
50.78 – 50.84 Mb
Chr 8:
91.22 – 91.28 Mb
PubMed search [1] [2]

Cylindromatosis (turban tumor syndrome), also known as CYLD, is a human gene.[1]

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[1]

References

Further reading




Wikimedia Foundation. 2010.

Look at other dictionaries:

  • CYLD — can refer to:* Chapleau Airport, an airport in Ontario, Canada * Cylindromatosis, a human gene …   Wikipedia

  • Brooke-Spiegler-Syndrom — Das Brooke Spiegler Syndrom (Henry Ambrose Grundy Brooke, englischer Dermatologe, Manchester, 1854–1919; Eduard Spiegler, österreichischer Chemiker und Dermatologe, Wien, 1860–1908) ist eine seltene autosomal dominant erbliche Erkrankung, die mit …   Deutsch Wikipedia

  • Cylindromatosis — (turban tumor syndrome), also known as CYLD, is a human gene.cite web | title = Entrez Gene: CYLD cylindromatosis (turban tumor syndrome)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=1540| accessdate = ] …   Wikipedia

  • DNAJC5 — DnaJ (Hsp40) homolog, subfamily C, member 5 PDB rendering based on 2ctw …   Wikipedia

  • DNAJA3 — DnaJ (Hsp40) homolog, subfamily A, member 3 PDB rendering based on 2ctt …   Wikipedia

  • DNAJB6 — DnaJ (Hsp40) homolog, subfamily B, member 6 Identifiers Symbols DNAJB6; DJ4; DKFZp566D0824; DnaJ; FLJ42837; HHDJ1; HSJ 2; HSJ2; MGC1152; MGC117297; MRJ; MSJ 1 External IDs …   Wikipedia

  • DNAJA1 — DnaJ (Hsp40) homolog, subfamily A, member 1 Identifiers Symbols DNAJA1; DJ 2; DjA1; HDJ2; HSDJ; HSJ2; HSPF4; NEDD7; hDJ 2 External IDs …   Wikipedia

  • TRAF interacting protein — TRAF interacting protein, also known as TRAIP, is a human gene.cite web | title = Entrez Gene: TRAIP TRAF interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=10293| accessdate = ] PBB… …   Wikipedia

  • DNAJA2 — DnaJ (Hsp40) homolog, subfamily A, member 2 Identifiers Symbols DNAJA2; CPR3; DJ3; DJA2; DNAJ; DNJ3; HIRIP4; PRO3015; RDJ2 External IDs …   Wikipedia

  • GroES — Heat shock 10kDa protein 1 (chaperonin 10) Identifiers Symbols HSPE1; CPN10; EPF; GROES; HSP10 External IDs …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.