Conserved non-coding sequence
CNSs in plants and animals are highly associated with transcription factor binding sites and other cis-acting regulatory elements. Conserved non-coding sequences can be important sites of evolutionary divergence as mutations in these regions may alter the regulation of conserved genes, producing species-specific patterns of gene expression.
- ^ a b Hardison, RC. (Sep 2000). "Conserved noncoding sequences are reliable guides to regulatory elements.". Trends Genet 16 (9): 369–72. PMID 10973062. http://www.euchromatin.org/Hardison1.htm.
- ^ Glazko, GV.; Koonin, EV.; Rogozin, IB.; Shabalina, SA. (Mar 2003). "A significant fraction of conserved noncoding DNA in human and mouse consists of predicted matrix attachment regions.". Trends Genet 19 (3): 119–24. PMID 12615002.
- ^ Prabhakar, S.; Noonan, JP.; Pääbo, S.; Rubin, EM. (Nov 2006). "Accelerated evolution of conserved noncoding sequences in humans.". Science 314 (5800): 786. doi:10.1126/science.1130738. PMID 17082449.
Wikimedia Foundation. 2010.
Look at other dictionaries:
Non-coding RNA — A non coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. Less frequently used synonyms are non protein coding RNA (npcRNA), non messenger RNA (nmRNA) and functional RNA (fRNA). The term small RNA (sRNA) is… … Wikipedia
Long non-coding RNA — Long noncoding RNAs (long ncRNAs) are generally considered (somewhat arbitrarily) as non protein coding transcripts longer than 200 nucleotides. This limit is due to practical considerations including the separation of RNAs in common experimental … Wikipedia
Conserved sequence — Residues conserved among various G protein coupled receptors are highlighted in green. In biology, conserved sequences are similar or identical sequences that occur within nucleic acid sequences (such as RNA and DNA sequences), protein sequences … Wikipedia
Non-homologous end joining — (NHEJ) is a pathway that repairs double strand breaks in DNA. NHEJ is referred to as non homologous because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a… … Wikipedia
Noncoding DNA — In genetics, noncoding DNA describes components of an organism s DNA sequences that do not encode for protein sequences. In many eukaryotes, a large percentage of an organism s total genome size is noncoding DNA, although the amount of noncoding… … Wikipedia
Comparative regulatory genomics database — CORG Content Description conserved Non coding DNA Contact Research center Max Planck Institute … Wikipedia
CNS — may refer to: Contents 1 Science and medicine 2 Education 3 Organisations 4 Media 5 Other … Wikipedia
Junk DNA — In molecular biology, junk DNA is a provisional label for the portions of the DNA sequence of a chromosome or a genome for which no function has been identified. Scientists expect to find functions for some, but not all,Fact|date=September 2008… … Wikipedia
Human genome — The human genome is the genome of Homo sapiens , which is stored on 23 chromosome pairs. Twenty two of these are autosomal chromosome pairs, while the remaining pair is sex determining. The haploid human genome occupies a total of just over 3… … Wikipedia
Геном человека/temp — Геном человека это геном биологического вида Homo sapiens . В нормальной ситуации у человека может присутствовать 24 различных хромосомы (22+X+Y): 22 из них не зависят от пола (аутосомные хромосомы), 2 X хромосома и Y хромосома зависят от пола.… … Википедия