Claude's syndrome Classification and external resources ICD-10 G46.3 ICD-9 352.6 DiseasesDB 33869 MeSH D020526
Claude's syndrome is a form of brainstem stroke syndrome characterized by the presence of an oculomotor nerve palsy, contralateral hemiparesis, contralateral ataxia, and contralateral hemiplegia of the lower face, tongue, and shoulder.
Cause and presentation
Claude's syndrome is caused by midbrain infarction as a result of occlusion of a branch of the posterior cerebral artery. This lesion is usually a unilateral infarction of the red nucleus and cerebral peduncle, affecting several structures in the midbrain including:
Structure damaged Effect dentatorubral fibers contralateral ataxia corticospinal tract fibers contralateral hemiparesis corticobulbar tract fibers contralateral hemiplegia of lower facial muscles, tongue, and shoulder oculomotor nerve fibers ipsilateral oculomotor nerve palsy with a drooping eyelid and fixed wide pupil pointed down and out; probable diplopia
It is very similar to Benedikt's syndrome.
- Wallenberg's syndrome
- Moritz Benedikt
- ^ 691339295 at GPnotebook
- ^ Dhanjal T, Walters M, MacMillan N (2003). "Claude's syndrome in association with posterior cerebral artery stenosis". Scottish Medical Journal 48 (3): 91–92. PMID 12968516. http://www.smj.org.uk/0803/claude.htm.
- ^ Claude H, Loyez M (1912). "Ramollissement du noyau rouge". Rev Neurol (Paris) 24: 49–51.
CNS disease, Vascular disease: Cerebrovascular diseases (G45–G46 and I60–I69, 430–438) Brain ischemia/
(ischemic stroke/TIA)precerebral: Anterior spinal artery syndrome · Vertebrobasilar insufficiency (Subclavian steal syndrome)brainstem: medulla (Medial medullary syndrome, Lateral medullary syndrome) · pons (Medial pontine syndrome/Foville's, Lateral pontine syndrome/Millard-Gubler) · midbrain (Weber's, Benedikt, Claude's)General
Aneurysm Other/general Lesions of spinal cord and brain Spinal cord/
BrainstemMedulla (CN 8, 9, 10, 12)Pons (CN 5, 6, 7, 8)Midbrain (CN 3, 4)Other Cerebellum Basal ganglia Cortex Other
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