Chitinase A N-terminal domain

ChitinaseA_N
PDB 1edq EBI.jpg
crystal structure of chitinase a from s. marcescens at 1.55 angstroms
Identifiers
Symbol ChitinaseA_N
Pfam PF08329
Pfam clan CL0159
InterPro IPR013540
SCOP 1ctn

In molecular biology, the chitinase A N-terminal domain is found at the N-terminus of a number of bacterial chitinases and similar viral proteins. It is organised into a fibronectin III module domain-like fold, comprising only beta strands. Its function is not known, but it may be involved in interaction with the enzyme substrate, chitin.[1][2] It is separated by a hinge region from the catalytic domain; this hinge region is probably mobile, allowing the N-terminal domain to have different relative positions in solution.[1]

References

  1. ^ a b Perrakis A, Tews I, Dauter Z, Oppenheim AB, Chet I, Wilson KS, Vorgias CE (December 1994). "Crystal structure of a bacterial chitinase at 2.3 A resolution". Structure 2 (12): 1169–80. PMID 7704527. 
  2. ^ Perrakis A, Ouzounis C, Wilson KS (1997). "Evolution of immunoglobulin-like modules in chitinases: their structural flexibility and functional implications". Fold Des 2 (5): 291–4. PMID 9377712. 

This article includes text from the public domain Pfam and InterPro IPR013540


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Carbohydrate-binding module — CBM 1 three dimensional structures of three engineered cellulose binding domains of cellobiohydrolase i from trichoderma reesei, nmr, 18 structures Identifiers Symbol CBM 1 …   Wikipedia

  • Life Sciences — ▪ 2009 Introduction Zoology       In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… …   Universalium

  • Хитиназа — Хитиназы (КФ 3.2.1.14) это ферменты, катализирующие деградацию хитина, действующие наиболее часто как эндоферменты, отщепляя хитоолигосахариды длиной в 2 6 N ацетилглюкозаминовых остатков [1]. Хитиназы относятся к группе О гликозидных гидролаз,… …   Википедия

  • Хитиназы — Хитиназа из семян ячменя Хитиназы (КФ 3.2.1.14)  это ферменты, катализирующие деградацию …   Википедия

  • Glycogen debranching enzyme — Amylo alpha 1, 6 glucosidase, 4 alpha glucanotransferase Identifiers Symbols AGL; GDE External IDs …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.