Miller Fisher

Charles Miller Fisher, usually known as Miller Fisher (born December 5, 1913, Waterloo, Ontario) is a neurologist.[1] Trained in Canada, he spent 1949 at Massachusetts General Hospital, followed by several years in Montreal. In 1954 he returned to Massachusetts General on the stroke service, beginning a long career in stroke neurology.[2] In 1956 he reported the variant of Guillain–Barré syndrome that now carries his name.[3] Fisher was the recipient of the Royal College of Physicians of Canada's Prize in Medicine in 1952, and entered the Canadian Medical Hall of Fame in 1998.

He contributed greatly to the understanding of stroke, more specifically carotid artery disease[1][2] and lacunar infarcts and their syndromes. With regards too the lacunar syndromes he described the concept,[4] the "pure motor stroke",[5] the "pure sensory stroke",[6] and the mechanism underlying the different stroke syndromes.[7][8][9] He contributed towards the current use of anticoagulants for stroke prevention in atrial fibrillation.[2] He made a number of contributions to the understanding of cervical artery dissection (carotid artery dissection and vertebral artery dissection) in the 1970s,[2] and that of subarachnoid hemorrhage due to cerebral aneurysms.[2]


  1. ^ a b Estol CJ (March 1996). "Dr C. Miller Fisher and the history of carotid artery disease". Stroke 27 (3): 559–66. PMID 8610329. 
  2. ^ a b c d e Fisher CM (November 2001). "A career in cerebrovascular disease: a personal account". Stroke 32 (11): 2719–24. doi:10.1161/hs1101.098765. PMID 11692045. 
  3. ^ Fisher CM (1956). "An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmolplegia, ataxia and areflexia)". N. Engl. J. Med. 255 (2): 57–65. doi:10.1056/NEJM195607122550201. PMID 13334797. 
  4. ^ Fisher CM (August 1965). "Lacunes: small, deep cerebral infarcts". Neurology 15: 774–84. PMID 14315302. 
  5. ^ Fisher CM, Curry HB (July 1965). "Pure motor hemiplegia of vascular origin". Arch. Neurol. 13: 30–44. PMID 14314272. 
  6. ^ Fisher CM (January 1965). "Pure sensory stroke involving face, arm and leg". Neurology 15: 76–80. PMID 14257831. 
  7. ^ Fisher CM (December 1968). "The arterial lesions underlying lacunes". Acta Neuropathol. 12 (1): 1–15. doi:10.1007/BF00685305. PMID 5708546. 
  8. ^ Fisher CM (August 1982). "Lacunar strokes and infarcts: a review". Neurology 32 (8): 871–6. PMID 7048128. 
  9. ^ Fisher CM (1991). "Lacunar infarcts: a review". Cerebrovasc Dis 1 (6): 311–20. doi:10.1159/000108861. 

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  • Syndrome de Miller-Fisher — Le syndrome de Miller Fisher, ou syndrome de Fisher, ou SMF, est une variante du syndrome de Guillain Barré, caractérisée par un manque de coordination des mouvements volontaires (ataxie) une absence de réflexes aréflexie une paralysie des des… …   Wikipédia en Français

  • síndrome de MILLER-FISHER — polineuropatía muy poco frecuente, que se considera como una variante del síndrome de Guillain Barre, que se caracteriza por ataxia, parálisis de los músculos oculares (oftalmoplegia) y arreflexia. Esta condición suele ir precedida de una… …   Diccionario médico

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