Terazosin

drugbox
IUPAC_name = [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl) piperazin-1-yl] - tetrahydrofuran-2-yl-methanone



CAS_number = 63590-64-7
ATC_prefix = G04
ATC_suffix = CA03
ATC_supplemental =
PubChem = 5401
DrugBank = APRD00667
C=19 | H=25 | N=5 | O=4
molecular_weight = 387.433 g/mol
bioavailability =
protein_bound = 90-94%
metabolism =
elimination_half-life = 12 hours
pregnancy_category =
legal_status =
routes_of_administration =

Terazosin (Hytrin) is a selective alpha 1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It also acts to lower the blood pressure, and is therefore a drug of choice for men with hypertension and prostate enlargement.

It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.

Most common side effects include dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion or dry eyes, but they generally go away after only a few days of use. Therapy should always be started with a low dose to avoid first dose phenomenon. [ [http://www.rxlist.com/cgi/generic/teraz_wcp.htm Hytrin (Terazosin Hcl) drug warnings and precautions - prescription drugs and medications at RxList ] ] Sexual side effects are rare, but may include priapism or erectile dysfunction.

References


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Terazosin — Strukturformel Allgemeines Freiname Terazosin Andere Namen …   Deutsch Wikipedia

  • terazosin — A drug used to treat urinary problems caused by an enlarged prostate. It is also used to treat high blood pressure and is being studied in the treatment of other conditions. Terazosin relaxes muscle tissue in blood vessels and in the prostate. It …   English dictionary of cancer terms

  • terazosin — noun A selective alpha 1 antagonist that is used to help treat an enlarged prostate and to help lower blood pressure …   Wiktionary

  • terazosin — te·ra·zo·sin tə rā zə .sin n an alpha adrenergic blocking agent administered orally in the form of its hydrated hydrochloride C19H25N5O4·HCl·2H2O esp. in the treatment of benign prostatic hyperplasia and hypertension see hytrin …   Medical dictionary

  • terazosin — noun antihypertensive drug (trade name Hytrin) used to treat high blood pressure • Syn: ↑Hytrin • Usage Domain: ↑trade name (for: ↑Hytrin) • Hypernyms: ↑antihypertensive, ↑ …   Useful english dictionary

  • terazosin hydrochloride — A drug used to treat urinary problems caused by an enlarged prostate. It is also used to treat high blood pressure and is being studied in the treatment of other conditions. Terazosin hydrochloride relaxes muscle tissue in blood vessels and in… …   English dictionary of cancer terms

  • terazosin hydrochloride — A peripherally acting antiadrenergic used to treat benign prostatic hypertrophy and hypertension. * * * ter·a·zo·sin hy·dro·chlo·ride (tər aґzo sin) [USP] an alpha1 adrenergic blocking agent used in the treatment of hypertension and benign… …   Medical dictionary

  • Tamsulosin — Systematic (IUPAC) name (R) 5 (2 {[2 (2 ethoxyphenoxy)ethyl]amino}propyl) 2 methoxybenzene 1 sulfonamide Clinical data …   Wikipedia

  • Adrenergic receptor — Epinephrine Norepinephrine The adrenergic receptors (or adrenoceptors) are a class of met …   Wikipedia

  • Doxazosin — Systematic (IUPAC) name (RS) 2 {4 [(2,3 dihydro 1,4 benzodioxin 2 yl)carbonyl]piperazin 1 yl} 6,7 dimethoxyquinazolin 4 amine Clinical data Trade names …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.