Earth Metabolic Design Laboratories
Earth Metabolic Design Laboratories was founded in 1984 by three psychedelic therapists, Alise Agar,
Rick Doblin, and Deborah Harlow, to support psychedelic research. [Holland, Julie "MDMA's Promise as a Prescription Medicine: an interview with Rick Doblin, Ph.D. In: Holland, Julie. Ecstasy: the Complete Guide, Inner Traditions International, 2001; ISBN 0-89281-857-3, pages 369-386.] It was formed while MDMA was still legal and the organization coordinated the activities of therapists, scientists, lawyers, and others to respond to the DEA's proposed placement of the drug in Schedule I. The organization requested that the DEA hold a hearing before scheduling. Among other achievements, it sponsored a study (coauthored by Doblin) of the toxicity of MDMAwhen given for 30-days to dogs and rodents [ [http://www.ncbi.nlm.nih.gov/pubmed/2887476 Frith CH, Chang LW, Lattin DL, Walls RC, Hamm J, Doblin R. Toxicity of methylenedioxymethamphetamine (MDMA) in the dog and the rat. Fundam Appl Toxicol. 1987 Jul;9(1):110-9. ] ] and an unblinded study of the effects of MDMAin twenty-one humans [ [http://www.erowid.org/references/refs_view.php?A=ShowDoc1&ID=548 Downing J. The psychological and physiological effects of MDMA on normal volunteers. J Psychoactive Drugs. 1986 Oct-Dec;18(4):335-40.] ] This latter publication was conducted in 1984 and was the first scientific study of the physiological effects of MDMA in humans. The organization apparently became inactive shortly thereafter and Doblin went on to focus his energies on forming a 'psychedelic orphan drug pharmaceutical company' that, in 1986, was named the Multidisciplinary Association for Psychedelic Studies[ [http://www.maps.org/dea-mdma/pdf/0171.PDF Doblin, Rick. A Proposal forOrphan Pharmaceuticals Inc. A Psychedelic Medicine Pharmaceutical Corporation] ] .
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