Rate of infusion

In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug "should" be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective.

Abbreviations include Kin, cite web |url=http://www.chm.davidson.edu/erstevens/iv%20inf%20Cp%20v%20t/iv%20inf%20Cp%20v%20t.html |title=Cp vs time - iv infusion |format= |work= |accessdate=] K0, cite web |url=http://www.boomer.org/c/p3/c15/c1502.html |title=Chapter 15.2 - Continuous IV Infusion - Steady State |format= |work= |accessdate=] or R0.

It can be calculated as the steady-state concentration in the plasma * the clearance.

ample values and equations

References


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