Gacyclidine

Drugbox
IUPAC_name = 1- [(1R,2S)-2-methyl-1-thiophen-2-ylcyclohexyl] piperidine


width= 150
CAS_number= 68134-81-6
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PubChem= 176265
DrugBank=
C=16 | H=25 | N=1 | S=1
molecular_weight = 263.4414 g/mol
bioavailability=
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Gacyclidine is a non-competitive NMDA antagonist and produces effects similar to PCP in animals. It is a derivative of Tenocyclidine. [Hirbec H, Gaviria M, Vignon J. Gacyclidine: a new neuroprotective agent acting at the N-methyl-D-aspartate receptor. "CNS Drug Reviews". 2001 Summer;7(2):172-98.] [ Hirbec H, Mausset AL, Kamenka JM, Privat A, Vignon J. Re-evaluation of phencyclidine low-affinity or "non-NMDA" binding sites. "J Neurosci Res". 2002 May 1;68(3):305-14.]

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