Large cell lymphoma

One classification system for lymphomas divides the diseases according to the size of the white blood cells that has turned cancerous. The large cell lymphomas have large cells. A large cell, in this context, has a diameter of 17 to 20 µm.cite book
author=Turgeon, Mary Louise
title=Clinical hematology: theory and procedures
publisher=Lippincott Williams & Wilkins
location=Hagerstown, MD
year=2005
pages=221
isbn=0-7817-5007-5
] Other groups of lymphomas in this system are the small cell lymphomas and mixed cell lymphomas.

Diffuse large B cell lymphoma is the most common of the large cell lymphomas. Many other B cell lymphomas feature large cells:

* Angiocentric lymphoma
* Burkitt’s lymphoma
* Follicular large cell lymphoma
* Immunoblastic lymphoma
* Intravascular large cell lymphoma
* Primary mediastinal B cell lymphoma
* T-cell–rich B-cell lymphoma
* Primary splenic lymphoma (rare)
* Primary central nervous system lymphomas, which are often diffuse large B cell lymphomas

Less commonly, a large cell lymphoma may feature T cells. Anaplastic large cell lymphoma is an example of a large cell lymphoma that involves T cells. Of the large-cell T-cell lymphomas, it has the best prognosis.

References


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • large cell lymphoma — any of several types of non Hodgkin lymphoma characterized by formation of malignant large lymphocytes in a diffuse pattern; some varieties contain exclusively one type of cell, such as lymphoblasts or cleaved or uncleaved follicular center cells …   Medical dictionary

  • large-cell lymphoma — Highly malignant group of tumours arising from transformed lymphocytes or myeloid precursors. Cell of origin often obscure …   Dictionary of molecular biology

  • Anaplastic large cell lymphoma — DiseaseDisorder infobox Name = PAGENAME ICD10 = ICD9 = ICDO = ICDO|9714|3 Caption = OMIM = MedlinePlus = eMedicineSubj = derm eMedicineTopic = 534 DiseasesDB = MeshID = D017728 Anaplastic large cell lymphoma (ALCL) is a type of non Hodgkin… …   Wikipedia

  • Follicular large cell lymphoma — is a rare type of non Hodgkin lymphoma (cancer of the lymphatic system) with large cells that look cleaved (split) or non cleaved under the microscope. It is an indolent (slow growing) type of lymphoma. External links *… …   Wikipedia

  • anaplastic large cell lymphoma — in a former system of classification, a type of large cell lymphoma in which cells are anaplastic and growth is sinusoidal; called also Ki 1 l …   Medical dictionary

  • diffuse mixed small and large cell lymphoma — a type of lymphoma that mixes the small cleaved cell and large cell varieties; it is similar to the diffuse, large cell type and has an intermediate grade of malignancy …   Medical dictionary

  • primary cutaneous anaplastic large cell lymphoma — a rare type of cutaneous T cell lymphoma characterized by localized nodules, plaques, or tumors …   Medical dictionary

  • follicular large cell lymphoma — A rare type of non Hodgkin lymphoma (cancer of the lymphatic system) with large cells that look cleaved (split) or non cleaved under the microscope. It is an indolent (slow growing) type of lymphoma …   English dictionary of cancer terms

  • follicular mixed small cleaved and large cell lymphoma — a type of non Hodgkin lymphoma with a mixture of small cleaved, large cleaved, and large uncleaved cells; the percentage of large cells is noticeable but less than 50 per cent of the tumor. It has a low grade of malignancy …   Medical dictionary

  • anaplastic large cell lymphoma — An aggressive (fast growing) type of non Hodgkin’s lymphoma that is usually of the T cell type. The cancer cells express a marker called CD30 or Ki 1 on the surface, and may appear in the lymph nodes, skin, bones, soft tissues, lungs, or liver …   English dictionary of cancer terms

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.