Tegafur


Tegafur

Drugbox
IUPAC_name = 5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione



CAS_number = 17902-23-7
CAS_supplemental =
ATC_prefix = L01
ATC_suffix = BC03
ATC_supplemental =
PubChem = 5386
DrugBank =
chemical_formula =
C=8 | H=9 | F=1 | N=2 | O=3
molecular_weight = 200.16 g/mol
smiles = C1CC(OC1)N2C=C(C(=O)NC2=O)F
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
legal_AU =
legal_CA =
legal_UK =
legal_US =
legal_status = Rx-only
routes_of_administration = Oral

Tegafur (INN) is a chemotherapeutic 5-FU prodrug used in the treatment of cancers. It is a component of Tegafur-uracil. When metabolized, it becomes 5-FU.

ee also

*Tegafur-uracil


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Look at other dictionaries:

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  • tegafur — noun A particular drug used to treat cancer …   Wiktionary

  • tegafur — teg·a·fur (tegґə fər) an investigational cancer chemotherapeutic agent, which is 5 fluorouracil (5 FU) attached to a tetrahydrofuran moiety analogous to the ribose and deoxyribose moieties in the active metabolites of 5 FU. It acts like …   Medical dictionary

  • tegafur — An anticancer drug that belongs to the family of drugs called antimetabolites …   English dictionary of cancer terms

  • Tegafur-uracil — is a chemotherapy drug used in the treatment of cancer, primarily bowel cancer. It is also called UFT or UFUR. [ [http://www.cancerbackup.org.uk/Treatments/Chemotherapy/Individualdrugs/Tegafur uracil Tegafur uracil (Uftoral) : Cancerbackup ] ]… …   Wikipedia

  • tegafur-uracil — A substance being studied in the treatment of some types of cancer. It is a combination of tegafur and uracil. The tegafur is taken up by the cancer cells and breaks down into 5 FU, a substance that kills tumor cells. The uracil causes higher… …   English dictionary of cancer terms

  • tegafur/uracil — see fluoropyrimidine, fluorouracil …   The new mediacal dictionary

  • Ftorafur — A substance being studied in the treatment of some types of cancer. It is a combination of tegafur and uracil. The tegafur is taken up by the cancer cells and breaks down into 5 FU, a substance that kills tumor cells. The uracil causes higher… …   English dictionary of cancer terms

  • UFT — A substance being studied in the treatment of some types of cancer. It is a combination of tegafur and uracil. The tegafur is taken up by the cancer cells and breaks down into 5 FU, a substance that kills tumor cells. The uracil causes higher… …   English dictionary of cancer terms


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