Children's Hospital Oakland Research Institute
Children's Hospital Oakland Research Institute (CHORI) is a biomedical research institute affiliated with California’s pediatric medical center, Children's Hospital & Research Center Oakland.
CHORI is based in Oakland, California operating a 100,000-square-foot (9,300 m2) biomedical research facility that houses 300 staff members. It includes six research centers conducting focused research on cancer, genetics, immunobiology and vaccine development, nutrition and metabolism, prevention of obesity, cardiovascular disease, and diabetes, sickle cell disease and thalassemia.
The National Institutes of Health is CHORI's primary funding source.
- Center for Cancer
- Center for Genetics
- Center for Immunobiology & Vaccine Development
- Center for Nutrition & Metabolism
- Center for Prevention of Obesity, Cardiovascular Disease & Diabetes
- Center for Sickle Cell Disease & Thalassemia
- BACPAC Resource Center
- Genetic Testing
- Mass Spectrometry Laboratory
- Sibling Donor Cord Blood
CHORI’s translational research applications include providing cures for blood diseases, developing new vaccines for infectious diseases, and discovering new treatment protocols for previously fatal or debilitating conditions such as cancers, sickle cell disease and thalassemia, diabetes, asthma, HIV/AIDS, pediatric obesity, nutritional deficiencies, birth defects, hemophilia and cystic fibrosis. CHORI is also a teaching institute  with educational programs for high school, college, doctoral and post-doctoral students.
CHORI is the first research institute in North America to transplant and cure a child with alpha thalassemia major, a leading center for the use of cord blood and bone marrow transplantation in children with sickle cell anemia and thalassemia, and offers the only not-for-profit Sibling Donor Cord Blood Program in the world. The Research Institute’s recombinant DNA library contains over 20 million DNA samples that are used in research programs around the world.
CHORI began in the 1960s with a small group of scientists and initial financial support from Children’s Hospital Oakland and the family of Lt. Bruce Lyon. Founded as the Bruce Lyon Memorial Research Laboratory (BLMRL), it was the first research laboratory in Northern California dedicated exclusively to children’s diseases. BLMRL was renamed “CHORI,” the research branch of the newly named Children's Hospital & Research Center Oakland in 1986.
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