V-type ATPase

V-type ATPase
(= vacuolar ATPase)
One of three major classes of ion transport ATPase, characterized by a multi-subunit structure, and a lack of a phosphorylated intermediate. Pumps H+. Found in intracellular acidic vacuoles and in some proton-pumping epithelia (eg. intercalated cells of kidney). Sensitive to bafilomycin. Related to the F-type ATPase. See also P-type ATPase.

Dictionary of molecular biology. 2004.

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