Abundant cytoplasmic protein (55 kD), found mainly in two forms, a and b. A tubulin heterodimer (one a, one b ), constitutes the protomer for microtubule assembly. Multiple copies of tubulin genes are present (and are expressed) in most eukaryotic cells studied so far. The different tubulin isoforms seem, however, to be functionally equivalent. g -tubulin is localized in the centrosome and is involved in nucleation of microtubule assembly during the cell cycle. Highly conserved from yeast to mammals.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Tubulin — Tubulin, die ⇒ Mikrotubuli aufbauendes Protein; kommt als α Tubulin und als β Tubulin vor, die sich zu Dimeren zusammenlagern …   Deutsch wörterbuch der biologie

  • tubulin — tubulin. См. тубулин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • tubulin — [to͞o′byə lin΄, tyo͞o′byə lin] n. a protein in cells that polymerizes to form tiny tubules that are important in forming microtubules …   English World dictionary

  • Tubulin — A Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α tubulin and β tubulin, the proteins that make up microtubules. Each has a molecular weight of approximately 55… …   Wikipedia

  • Tubulin — ist ein ca. 55 kDa großes Protein, das in den Zellen von Eukaryonten vorkommt. Die häufigsten Formen des Tubulins, das α Tubulin und β Tubulin, sind Hauptbestandteil der Mikrotubuli. Je ein α und β Tubulin bilden in ihnen Hetero Dimere (s. Abb.) …   Deutsch Wikipedia

  • Tubulin — Tu|bu|lin [slat. tubulus = Röhrchen; ↑ in (3)], das; s, e: ein dimeres, aus zwei weitgehend identischen Untereinheiten (α u. β Tubulin, MG jeweils ca. 50 000) bestehendes Protein, das polymerisieren u. dabei die sog. Mikrotubuli (Leitstrukturen… …   Universal-Lexikon

  • tubulin — noun a) Any of a group of proteins used as the material for microtubules b) Specifically, the dimer of α tubulin and β tubulin …   Wiktionary

  • tubulin — A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α t. and β t.. SEE ALSO: dynein. t. tyrosine ligase an enzyme that covalently links a tyrosine to the C terminal glutamyl residue of t., coupled with the… …   Medical dictionary

  • tubulin — noun Etymology: tubule + 1 in Date: 1968 a globular protein that polymerizes to form microtubules …   New Collegiate Dictionary

  • tubulin — /tooh byeuh lin, tyooh /, n. Biochem. either of two globular proteins that form the structural subunits of microtubules. [1965 70; TUBULE + IN2] * * * …   Universalium

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