Condition in which there is defective platelet aggregation, though adherence is normal. See Glanzmann\'s thrombasthenia.

Dictionary of molecular biology. 2004.

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  • thrombasthenia — An abnormality of platelets characteristic of Glanzmann t.. SEE ALSO: Bernard Soulier syndrome. SYN: thromboasthenia. [thromb + G. astheneia, weakness] Glanzmann t. [MIM*273800] a hemorrhagic diathesis characterized by n …   Medical dictionary

  • thrombasthenia — throm·bas·the·nia …   English syllables

  • thrombasthenia — n. a hereditary blood disease in which the function of the platelets is defective although they are present in normal numbers. The manifestations are identical to those of thrombocytopenic purpura …   The new mediacal dictionary

  • thrombasthenia — noun a rare autosomal recessive disease in which the platelets do not produce clots in the normal way and hemorrhage results • Hypernyms: ↑autosomal recessive disease, ↑autosomal recessive defect * * * ˌthrämbəsˈthēnēə noun Etymology: New Latin,… …   Useful english dictionary

  • Glanzmann's thrombasthenia — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 5224 ICD10 = ICD10|D|69|1|d|65 ICD9 = ICD9|287.1 ICDO = OMIM = 187800 OMIM mult = OMIM2|273800 | MedlinePlus = eMedicineSubj = med eMedicineTopic = 872 MeshID = D013915 Glanzmann s… …   Wikipedia

  • Glanzmann thrombasthenia (disease) — Glanz·mann thrombasthenia (disease) (glahntsґmən) [Eduard Glanzmann, Swiss pediatrician, 1887–1959] see thrombasthenia …   Medical dictionary

  • Glanzmann thrombasthenia — a hereditary platelet abnormality characterized by defective clot retraction, prolonged bleeding time, and related symptoms such as epistaxis and inappropriate bleeding. Clinically there is abnormal glass adhesion and impaired aggregation to ADP …   Medical dictionary

  • Glanzmann's thrombasthenia — Platelet dysfunction in which aggregation is deficient. A specific glycoprotein complex (IIb/IIIa) is absent from the plasma membrane: this seems to be the fibronectin/fibrinogen receptor and is a b3 integrin …   Dictionary of molecular biology

  • constitutional thrombocytopathy — thrombasthenia …   Medical dictionary

  • Coagulation — This article is about blood clotting. For other meanings see Coagulation (disambiguation). Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis, the cessation of blood loss from a damaged vessel,… …   Wikipedia

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