A group of neuropeptide hormones including substance P, substance K (neurokinin A) and neurokinin B in mammals, eledoisin from Octopus and physalaemin (amphibian). All have 10 or 11 residues with a common -FXGLM-NH2 ending. Elicit a wide range of responses from neurons, smooth muscle, endothelium, exocrine glands and cells of the immune system; effects similar in many ways to bradykinin and serotonin.

Dictionary of molecular biology. 2004.

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