(= Shp-1, Shp-2)
Protein tyrosine phosphatases with SH2 domains. Are recruited to ITIM motif of receptor tyrosine kinases and play an important role in the control of cytokine signalling. Shp-1 is important in regulating antigen responses in T-cells and the mouse mutant ( motheaten ) is immunosuppressed. Shp-2 is more ubiquitously expressed and functions downstream of a variety of growth factor receptors and has a role in cell spreading and migration; the homozygous mouse knockout is embryonic lethal.

Dictionary of molecular biology. 2004.

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  • SHP — steht für: Samoczynne hamowanie pociągu („Selbstständiges Bremsen des Zuges“), ein polnisches Zugsicherungssystem; siehe SHP (Zugsicherung) Shaft Horse Power, englisch für „Wellenpferdestärke“, eine der Pferdestärke verwandte Maßeinheit Shapefile …   Deutsch Wikipedia

  • SHP — or shp may refer to: * Saint Helena pound, the currency of the British overseas territories of Saint Helena and Ascension Island * Seton Hall Preparatory School, a school in West Orange, New Jersey * Shaft horsepower, the power delivered to the… …   Wikipedia

  • shp — abbrev. shaft horsepower …   English World dictionary

  • SHP — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom.   Sigles d’une seule lettre   Sigles de deux lettres > Sigles de trois lettres   Sigles de quatre lettres …   Wikipédia en Français

  • shp — See shaft horsepower. Also, SHP, S.H.P., s.hp., s.h.p. * * * …   Universalium

  • SHP — abbreviation Usage: often not capitalized shaft horsepower * * * See shaft horsepower. Also, SHP, S.H.P., s.hp., s.h.p …   Useful english dictionary

  • shp — abbreviation shaft horsepower …   New Collegiate Dictionary

  • SHP — In currencies, this is the abbreviation for the St. Helana Pound. The currency market, also known as the Foreign Exchange market, is the largest financial market in the world, with a daily average volume of over US $1 trillion …   Investment dictionary

  • SHP — Shop (Business » Firms) * St Helena Pound (Regional » Currencies) * Southern Highlands Province (Regional) * Steed Hammond Paul (Business » Firms) * Printmaster Icon library (Computing » File Extensions) * Schein Pharmaceutical Inc (Business »… …   Abbreviations dictionary

  • SHP — Schonlein Henoch purpura; secondary hyperparathyroidism; Skaraborg Hypertension Project; state health plan …   Medical dictionary

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