sex-linked disorder


sex-linked disorder
A genetic defect, usually due to a gene on the unpaired portion of the X chromosome. Recessive X-linked alleles are fully expressed in the heterogametic sex because they can have only one copy of the gene. Thus X-linked mutant disorders are more common in human males than in females.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • sex-linked disorder — noun any disease or abnormality that is determined by the sex hormones hemophilia is determined by a gene defect on an X chromosome • Hypernyms: ↑chromosomal aberration, ↑chromosomal anomaly, ↑chrosomal abnormality, ↑chromosonal disorder •… …   Useful english dictionary

  • sex chromosome — Genetics. a chromosome, differing in shape or function from other chromosomes, that determines the sex of an individual. [1910 15] * * * Either of a pair of chromosomes that determine whether an individual is male or female. The sex chromosomes… …   Universalium

  • Sex differences in humans — Male and female anatomy. Note that these models have had body hair and male facial hair removed and head hair trimmed. A sex difference is a distinction of biological and/or physiological characteristics associated with either males or females of …   Wikipedia

  • Sex and illness — A sex specific illness is an illness that occurs only in people of one sex. In a more general sense, sex related illnesses are illnesses that are more common to one sex, or which manifest differently in each sex. For example, certain autoimmune… …   Wikipedia

  • Sex and psychology — This article is about psychology and the male and female biological sexes. For information about human sexual perceptions, see Human sexuality. Research on sex and psychology investigates cognitive and behavioral differences between men and women …   Wikipedia

  • disorder — A disturbance of function, structure, or both, resulting from a genetic or embryonic failure in development or from exogenous factors such as poison, trauma, or disease. adjustmen …   Medical dictionary

  • chromosonal disorder — noun any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities • Syn: ↑chromosomal aberration, ↑chromosomal anomaly, ↑chrosomal abnormality • Hypernyms: ↑aberrance, ↑aberrancy, ↑aberration, ↑ …   Useful english dictionary

  • Neurodevelopmental disorder — A boy with microcephaly and his schoolmates. Microcephaly is a neurodevelopmental disorder. A neurodevelopmental disorder,[1] or disorder of neural devel …   Wikipedia

  • X-linked lymphoproliferative syndrome — (XLP syndrome, Duncan s disease) a hereditary disorder of the immune system caused by a defective sex linked gene carried on an X chromosome. There is uncontrolled proliferation of B lymphocyte in response to infection by the Epstein Barr virus,… …   Medical dictionary

  • X-linked lymphoproliferative syndrome — XLP syndrome; = Duncan s disease a hereditary disorder of the immune system caused by a defective sex linked gene carried on an X chromosome. There is uncontrolled proliferation of B lymphocytes in response to infection by the Epstein Barr virus …   The new mediacal dictionary


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