- Chronic inflammatory disease in which there is destruction of joints. Considered by some to be an autoimmune disorder in which immune complexes are formed in joints and excite an inflammatory response (complex-mediated hypersensitivity). Cell-mediated (Type IV) hypersensitivity also occurs, and macrophages accumulate. This in turn leads to the destruction of the synovial lining (see pannus).
Dictionary of molecular biology. 2004.
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rheumatoid arthritis — noun a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that… … Useful english dictionary
rheumatoid arthritis — [[t]ru͟ːmətɔɪd ɑː(r)θra͟ɪtɪs[/t]] N UNCOUNT Rheumatoid arthritis is a long lasting disease that causes your joints, for example your hands or knees, to swell up and become painful … English dictionary
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