(= phosphatase and tensin homolog deleted on chromosome ten; MMAC1/PTEN; TEP-1)
A protein tyrosine phosphatase with homology to tensin, is a tumour-suppressor gene on chromosome 10q23. Somatic mutations in PTEN occur in multiple tumours, most markedly glioblastomas. Germ-line mutations in PTEN are responsible for Cowden disease (CD), a rare autosomal dominant multiple-hamartoma syndrome. Mutated in MMAC1/PTEN (multiple advanced cancers 1/phosphatase and tensin) homologue.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • PTEN — Структура фосфатазы PTEN человека. Синим показан N концевой фосфатазный домен, красным С концевой С2 домен Обозначения Сим …   Википедия

  • PTEN — Bändermodell nach PDB 1D5R …   Deutsch Wikipedia

  • PTEN — may mean: * Patterson UTI Energy, Inc., which trades on the NASDAQ stock market under the symbol PTEN * Prime Time Entertainment Network * PTEN (gene), a human tumour suppressor gene on chromosome 10 …   Wikipedia

  • PTEN — un gen supresor de tumores constituído por una fosfatasa localizada en el cromosoma 10 (10q23) que actúa mediante una vía dependiente de Akt para suprimir la división celular y permitir la apoptosis. Su papel en la supresión de tumores se ha… …   Diccionario médico

  • Pten — (Ptenium), so v.w. Osmium …   Pierer's Universal-Lexikon

  • PTEN — Fosfatidilinositol 3,4,5 trisfosfato 3 fosfatasa PTEN humana. HUGO 9588 …   Wikipedia Español

  • PTEN — Patterson Energy, Inc. (Business » NASDAQ Symbols) Prime Time Entertainment Network (Community » Media) * Phosphatase/Tensin homolog deleted on chromosome 10 (Medical » Oncology) …   Abbreviations dictionary

  • PTEN — pentaerythritol tetranitrate …   Medical dictionary

  • PTEN — (Warner) Prime Time Entertainment Network …   Acronyms

  • PTEN — (Warner) Prime Time Entertainment Network …   Acronyms von A bis Z

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