A high molecular weight complex of protein and polysaccharide, characteristic of structural tissues of vertebrates, such as bone and cartilage, but also present on cell surfaces. Important in determining viscoelastic properties of joints and other structures subject to mechanical deformation. Glycosaminoglycans (GAGs), the polysaccharide units in proteoglycans, are polymers of acidic disaccharides containing derivatives of the amino sugars glucosamine or galactosamine.
Dictionary of molecular biology. 2004.
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Proteoglycan — Proteoglycans represent a special class of glycoproteins that are heavily glycosylated. They consist of a core protein with one or more covalently attached glycosaminoglycan (GAG) chain(s). These glycosaminoglycan chains are long, linear… … Wikipedia
proteoglycan — noun Etymology: International Scientific Vocabulary Date: 1968 any of a class of glycoproteins of high molecular weight that are found especially in the extracellular matrix of connective tissue … New Collegiate Dictionary
Proteoglycan — Proteoglykane sind ein wichtiger Bestandteil der Extrazellulären Matrix, sind aber auch an der Zelloberfläche und in intrazellulären sekretorischen Granula lokalisiert. Proteoglykane bilden eine Klasse von besonders stark glykosylierten… … Deutsch Wikipedia
proteoglycan — /proh tee oh gluy kan/, n. Biochem. a macromolecule composed of a polysaccharide joined to a polypeptide and forming the ground substance of connective tissue. [1969; PROTE(IN) + O + GLYC + an, var. of ANE] * * * … Universalium
proteoglycan — noun Any of many glycoproteins that have heteropolysaccharide side chains … Wiktionary
proteoglycan I — SYN: biglycan … Medical dictionary
proteoglycan — pro·teo·gly·can .prōt ē ə glī .kan n any of a class of glycoproteins of high molecular weight that are found in the extracellular matrix of connective tissue, are made up mostly of carbohydrate consisting of various polysaccharide side chains… … Medical dictionary
proteoglycan — [ˌprəʊtɪəʊ glʌɪkan] noun Biochemistry a compound consisting of a protein bonded to mucopolysaccharide groups, present especially in connective tissue … English new terms dictionary
proteoglycan — proteo·glycan … English syllables
proteoglycan — A molecule that contains both protein and glycosaminoglycans, which are a type of polysaccharide. Proteoglycans are found in cartilage and other connective tissues … English dictionary of cancer terms