(= PKC related kinase; PKN)
Serine/threonine kinases (120 kD). PRK-1 is found in hippocampus and is activated by phospholipids and arachidonic acid, binds to rho-GTP and possibly regulates cytoskeletal changes. PRK-2 (PKN-2; PAK-2) was isolated from U937 cells and foetal brain and is activated by cardiolipin and acidic phospholipids. Binds rac and rho which will activate its kinase activity, and interacts with SH3 domain of Nck and PLC g.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • PRK — Acronym for photorefractive keratectomy. * * * photorefractive keratectomy; primary rabbit kidney * * * PRK abbr photorefractive keratectomy * * * photorefractive keratectomy (see keratectomy). * * * photorefractive keratectomy …   Medical dictionary

  • PRK — abbreviation photorefractive keratectomy …   New Collegiate Dictionary

  • PRK — Park (Regional) * Park National Corporation (Business » AMEX Symbols) * Photo Refractive Keratotomy (Medical » Physiology) * Professional Research And Knowledge (Academic & Science » Universities) * Password Recovery Key (Computing » Security) *… …   Abbreviations dictionary

  • prk — ISO 639 3 Code of Language ISO 639 2/B Code : ISO 639 2/T Code : ISO 639 1 Code : Scope : Individual Language Type : Living Language Name : Parauk …   Names of Languages ISO 639-3

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