neuregulin


neuregulin
(= neu differentiation factor)
Growth factor of the epidermal growth factor family that induces growth and differentiation of epithelial, glial and muscle cells in culture. Receptor is a tyrosine kinase: will bind erbB3 which will heterodimerise with erbB2. Gene disruption is lethal during embryogenesis with heart malformation and defects in Schwann cells and neural ganglia. Neuregulin 1 and Neuregulin 2 show distinct expression patterns and mediate distinct biological processes.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Neuregulin 1 — PDB rendering based on 1hae …   Wikipedia

  • Neuregulin — family Structure of the epidermal growth factor like domain of heregulin alpha, a ligand for p180erbB 4.[1] Identifiers Sy …   Wikipedia

  • Neuregulin-1 — …   Википедия

  • neuregulin — noun Any of a family of proteins that have functions in the development of the nervous system …   Wiktionary

  • neuregulin — neu·reg·u·lin (n regґu lin) any of a group of proteins thought to be regulators of nerve and muscle development and of oncogenic transformation of epithelial cells …   Medical dictionary

  • NRG2 — Neuregulin 2 Identifiers Symbols NRG2; DON1; HRG2; NTAK External IDs OMIM:  …   Wikipedia

  • NRG3 — Neuregulin 3 Identifiers Symbols NRG3; HRG3; pro NRG3 External IDs OMIM:  …   Wikipedia

  • NRG4 — Neuregulin 4 Identifiers Symbols NRG4; DKFZp779N0541; DKFZp779N1944; HRG4 External IDs …   Wikipedia

  • Нейрегулин-3 — neuregulin 3 Обозначения Символы NRG3 Entrez Gene …   Википедия

  • Нейрегулин-1 — Обозначения Символы NRG1; HRGA, NDF, ARIA, GGF2, SMDF Entrez Gene …   Википедия


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