- nerve growth factor
A peptide (13.26 kD) of 118 amino acids (usually dimeric) with both chemotropic and chemotrophic properties for sympathetic and sensory neurons. Found in a variety of peripheral tissues, NGF attracts neurites to the tissues by chemotropism, where they form synapses. The successful neurons are then "protected" from neuronal death by continuing supplies of NGF. It is also found at exceptionally high levels in snake venom and male mouse submaxillary salivary glands, from which it is commercially extracted. NGF was the first of a family of nerve tropic factors to be discovered. Amino acids 1-81 show homology with proinsulin. Besides its peripheral actions, NGF selectively enhances the growth of cholinergic neurons that project to the forebrain and that degenerate in Alzheimer\'s disease.
Dictionary of molecular biology. 2004.
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Nerve growth factor — (beta polypeptide) Rendering of NGF from PDB 1SG1 … Wikipedia
Nerve Growth Factor — Der Nervenwachstumsfaktor (engl.: nerve growth factor, NGF) wurde in den 1950ern von Rita Levi Montalcini und Viktor Hamburger entdeckt und ist einer von vielen neurotrophen Faktoren. NGF gehört zur Gruppe der Neurotrophine. Funktion In der… … Deutsch Wikipedia
Nerve growth factor — is a substance that occurs naturally in the body which enhances the growth and survival of nerves of a certain type called cholinergic nerves. * * * nerve growth factor n a protein that promotes development of the sensory and sympathetic nervous… … Medical dictionary
Nerve Growth factor IB — Nuclear receptor subfamily 4, group A, member 1 PDB rendering based on 1cit … Wikipedia
nerve growth factor — noun a protein that is involved in the growth of peripheral nerve cells • Syn: ↑NGF • Hypernyms: ↑growth factor * * * noun : a protein that promotes development of the sensory and sympathetic nervous systems and is required for maintenance of… … Useful english dictionary
nerve growth factor — noun a functional protein complex required for the suvival, growth and specialization of certain types of neurons in vertebrates. They (trypsin like serine proteases) are also thought to be involved in the processing or activation of other… … Wiktionary
nerve growth factor — a protein (see growth factor), consisting of two polypeptide chains, that is required for the development and longevity of some neurones, including those in the sympathetic nervous system and some central nervous system and sensory neurones.… … Medical dictionary
nerve growth factor — NGF a protein (see growth factor), consisting of two polypeptide chains, that is required for the development and longevity of some neurones, including those in the sympathetic nervous system and some central nervous system and sensory neurones.… … The new mediacal dictionary
nerve growth factor — nerve′ growth fac tor n. phl biochem. a protein that promotes the growth, organization, and maintenance of sympathetic and some sensory nerve cells Abbr.: NGF • Etymology: 1965–70 … From formal English to slang
nerve growth factor — Biochem. a protein that promotes the growth, organization, and maintenance of sympathetic and some sensory nerve cells. Abbr.: NGF [1965 70] * * * … Universalium