Link proteins of basal lamina; consist of an A chain (400 kD) and two B chains (200 kD). Each subunit contains at least 12 repeats of the EGF-like domain. The first laminin studied was from mouse EHS cells, but it is now becoming clear that different forms of laminin occur. In laminin from placenta the A chain is replaced with merosin, in laminin found near the neuromuscular junction the B1 chain is replaced by s-laminin (synapse laminin). Laminin induces adhesion and spreading of many cell types and promotes the outgrowth of neurites in culture.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Laminin — is the major non collagenous component of the basal lamina, such as those on which cells of an epithelium sit.cite book |author=M. A. Haralson and John R. Hassell |title=Extracellular matrix: a practical approach |publisher=IRL Press… …   Wikipedia

  • laminin — [lam′i nin] n. Biochem. a large glycoprotein that binds epithelial cells to connective tissue * * * …   Universalium

  • laminin — [lam′i nin] n. Biochem. a large glycoprotein that binds epithelial cells to connective tissue …   English World dictionary

  • Laminin — Die Laminine sind kollagenähnliche Glykoproteine und ein Bestandteil der extrazellulären Matrix[1]. Laminine findet man in allen Basallaminae, und sie weisen Bindungsstellen für Zelloberflächenrezeptoren auf. Zusammen mit Kollagen Typ IV,… …   Deutsch Wikipedia

  • laminin — noun Etymology: lamina + 1 in Date: 1979 a glycoprotein component of connective tissue basement membrane that promotes cell adhesion …   New Collegiate Dictionary

  • laminin — noun Any of a class of glycoproteins found in the basement membranes of most animal tissue …   Wiktionary

  • laminin — A large multimeric glycoprotein component of the basement membrane; particularly its unstained laminae; a major protein component of the laminae of the renal glomerulus. * * * lam·i·nin lam ə nən n a glycoprotein …   Medical dictionary

  • Laminin — La|mi|nin [lat. lamina = Platte, Scheibe, Klinge; ↑ in (3)], das; s, e: Gruppenbez. für Glykoproteine vom MG ca. 850 000, die in der Basalmembran Rezeptorfunktionen wahrnehmen …   Universal-Lexikon

  • Laminin — Lamini̱n [zu ↑Lamina] s; s, e: Protein des Bindegewebes …   Das Wörterbuch medizinischer Fachausdrücke

  • laminin — lam·i·nin …   English syllables

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