inbred strain


inbred strain
Any strain of animal or plant obtained by a breeding strategy that tends to lead to homozygosity. Such breeding strategies include brother-sister mating and back-crossing of offspring with parents. See also congenic.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Inbred strain — Linear animals or inbred strains are animals of a particular species which are nearly identical to each other in genotype due to long inbreeding. Mating of brother sister pairs for 20 generations will result in lines that are roughly 98%… …   Wikipedia

  • Strain — can refer to: * Strain (biology), a variant of a plant, virus or bacterium; or an inbred animal used for experimental purposes * Strain (chemistry), a chemical stress of a molecule * Strain (continuum mechanics), the deformation of materials… …   Wikipedia

  • inbred line — noun (biology) A strain that has been inbred over many generations, its members being genetically identical or nearly so • • • Main Entry: ↑inbreed …   Useful english dictionary

  • strain — 1. A population of homogeneous organisms possessing a set of defined characteristics; in bacteriology, the set of descendants that retains the characteristics of the ancestor; members of a s. that subsequently differ from the original isolate are …   Medical dictionary

  • Strain (biology) — In biology, strain is a low level taxonomic rank used in three related ways.Microbiology/VirologyA strain is a genetic variant or subtype of a microorganism (e.g. virus or bacterium or fungus). For example, a flu strain is a certain biological… …   Wikipedia

  • BALB/c — Inbred strain of white (albino) mice. Used as a source for one of the various 3T3 cell lines …   Dictionary of molecular biology

  • incross — in·cross in .krȯs n 1) an individual produced by crossing inbred lines of the same breed or strain 2) a mating between individuals from inbred lines of the same breed or strain incross vt to interbreed (inbred lines of a breed or strain) * * *… …   Medical dictionary

  • congenic — Relating to an inbred strain of animals produced by repeated crossing of one gene line onto another inbred (isogenic) line. [con + G. genos, birth, + ic] * * * con·gen·ic (kən jenґik) [con + L. genus race, kind] pertaining to two inbred… …   Medical dictionary

  • NOG mouse — A NOG (NOD/Shi scid/IL 2Rγnull) mouse is a new generation of severely immunodeficient mouse, developed by Central Institute for Experimental Animals (CIEA) in 2000. The NOG mouse accepts heterologous cells much more easily compared with any other …   Wikipedia

  • Backcrossing — Not to be confused with Breeding back. Backcrossing is a crossing of a hybrid with one of its parents or an individual genetically similar to its parent, in order to achieve offspring with a genetic identity which is closer to that of the parent …   Wikipedia


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