(= heparin-binding epidermal growth factor)
HB-EGF, like amphiregulin, has a long N-terminal extension that seems to confer the ability to bind to heparin and also to other connective tissue macromolecules (glycosaminoglycans) and cell surface molecules such as CD44. Because it is immobilized the effective local concentration may be much higher and the effects may differ from those of soluble growth factors.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • Egf — {{{image}}}   Sigles d une seule lettre   Sigles de deux lettres > Sigles de trois lettres AAA à DZZ EAA à HZZ IAA à LZZ MAA à PZZ QAA à TZZ UAA à XZZ …   Wikipédia en Français

  • EGF — abbr. epidermal growth factor. * * * …   Universalium

  • EGF — [Abk. für engl. epidermal growth factor = epidermaler Wachstumsfaktor]; Syn.: Urogastron: aus tierischen Geweben bzw. aus Harn isolierbares Protein aus 53 Aminosäuren, das die Entwicklung u. Vermehrung von Zellen des Haut u. Schleimhautgewebes in …   Universal-Lexikon

  • EGF module-containing mucin-like hormone receptor — protein Name = egf like module containing, mucin like, hormone receptor like 1 caption = width = HGNCid = 3336 Symbol = EMR1 AltSymbols = TM7LN3 EntrezGene = 2015 OMIM = 600493 RefSeq = NM 001974 UniProt = Q14246 PDB = ECnumber = Chromosome = 19… …   Wikipedia

  • EGF-like domain — Pfam box Symbol = EGF Name = EGF like domain width = caption = Pfam= PF00008 InterPro= IPR006209 SMART= PROSITE = PDOC00021 SCOP = 1apo TCDB = OPM family= OPM protein= 1dan PDB=PDB3|1tpg :86 119 PDB3|1haf :182 221 PDB3|1hae :182 221PDB3|1hrf :182 …   Wikipedia

  • EGF — Die Abkürzung EGF steht für: American Eagle Airlines (ICAO Code), eine US amerikanische Fluggesellschaft Epidermal Growth Factor, ein Wachstumsfaktor in der Zellbiologie Europäischer Fonds für die Anpassung an die Globalisierung, ein Sozialfonds… …   Deutsch Wikipedia

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  • EGF — See epidermal growth factor, EGF like domain …   Dictionary of molecular biology

  • EGF-like domain — Region of 30 40 amino acids containing 6 cysteines found originally in EGF, and also in a range of proteins involved in cell signalling. Examples: TGF a, amphiregulin, urokinase, tissue plasminogen activator, complement C6 C9, fibronectin,… …   Dictionary of molecular biology

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