- growth cone
A specialized region at the tip of a growing neurite that is responsible for sensing the local environment and moving toward the neuron\'s target cell. Growth cones are hand-shaped, with several long filopodia that differentially adhere to surfaces in the embryo. Growth cones can be sensitive to several guidance cues, for example, surface adhesiveness, growth factors, neurotransmitters and electric fields (galvanotropism).
Dictionary of molecular biology. 2004.
Look at other dictionaries:
growth cone — n the specialized motile tip of an axon of a growing or regenerating nerve cell * * * a bulbous enlargement of the growing tip of an axon … Medical dictionary
growth cone — growth′ cone n. cbl a flattened neuronal area, at the ends of growing axons and dendrites, having radiating structures that guide the pathways of embryonic nerve fibers … From formal English to slang
Growth cone — Image of a fluorescently labeled growth cone extending from an axon F actin (red) microtubules (green). A growth cone is a dynamic, actin supported extension of a developing axon seeking its synaptic target. Their existence was originally… … Wikipedia
growth cone — noun Date: 1970 the specialized motile tip of an axon of a growing or regenerating neuron … New Collegiate Dictionary
growth cone — Cell Biol. a flattened area at the end of a growing axon or dendrite, having radiating filopodia and lemellopodia that function as guides for the outgrowth of embryonic nerve fibers. * * * … Universalium
growth cone — noun : the specialized motile tip of an axon of a growing or regenerating nerve cell * * * Cell Biol. a flattened area at the end of a growing axon or dendrite, having radiating filopodia and lemellopodia that function as guides for the outgrowth … Useful english dictionary
growth cone collapse — Loss of motile activity and cessation of advance by growth cones. There are now thought to be specific molecules that inhibit the motility of particular growth cones, and that are important in establishing correct pathways in developing nervous… … Dictionary of molecular biology
nerve growth cone — See growth cone … Dictionary of molecular biology
Cone — This disambiguation page lists articles associated with the same title. If an internal link led you here, you may wish to change the link to point directly to the intended article … Wikipedia
growth-associated proteins — (= GAPs) Group of developmentally regulated polypeptides thought to be critical for the formation of neural circuitry. The acidic membrane phosphoprotein GAP 43 is synthesized and transported down regenerating and developing axons; pp46 localized … Dictionary of molecular biology