gentamicin


gentamicin
A group of aminoglycoside antibiotics produced by Micromonospora spp. Members include the closely related gentamycins C1, C2 and C1a, together with gentamycin A. They inhibit protein synthesis on 70S ribosomes by binding to the 23S core protein of the small subunit, that is responsible for binding mRNA. Mode of action similar to that of kanamycin, neomycin, paromomycin, spectinomycin and streptomycin. Active against strains of the bacterium Pseudomonas aeruginosa.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Gentamicin — Systematic (IUPAC) name (3R,4R,5R) 2 {[(1S,2S …   Wikipedia

  • Gentamicin —   [Kurzwort] das, s, Gentamizin, aus Kulturfiltraten verschiedener Micromonospora Arten gewonnenes Breitbandantibiotikum aus der Gruppe der Aminoglykosidantibiotika; besteht im Wesentlichen aus drei Komponenten, die (ähnlich wie Streptomycin) aus …   Universal-Lexikon

  • gentamicin — gentamìcīn m <G gentamicína> DEFINICIJA farm. antibiotik širokog spektra, dobiva se iz aktinomicetne bakterije Micromonospora purpurea; primjenjuje se parenteralno u slučajevima gama negativnih infekcija ETIMOLOGIJA engl. gentian violet:… …   Hrvatski jezični portal

  • gentamicin — [jent΄ə mī′sin] n. [< gentian violet (color of the organism) + MYCIN] a broad spectrum antibiotic obtained from soil actinomycetes (genus Micromonospora), used in treating a wide variety of serious infections …   English World dictionary

  • Gentamicin — Wikipedia:Redaktion Chemie/ausgeblendete Strukturformel Allgemeines Freiname Gentamicin Andere Namen Gentamycin Summenformel Stoffgemisch …   Deutsch Wikipedia

  • gentamicin — noun Etymology: alteration of earlier gentamycin, from gentian violet + kanamycin; from the color of the actinomycete Date: 1963 a broad spectrum antibiotic mixture derived from an actinomycete (Micromonospora purpurea or M. echinospora) and… …   New Collegiate Dictionary

  • gentamicin — /jen teuh muy sin/, n. Pharm. a highly toxic broad spectrum antibiotic mixture of related aminoglycoside substances derived from the actinomycete bacterium Micromonospora purpurea, used in its sulfate form in the treatment of severe Gram negative …   Universalium

  • gentamicin — noun A glycoside antibiotic, derived from an actinomycete, used to treat bacterial infections …   Wiktionary

  • gentamicin — A broad spectrum antibiotic of the aminoglycoside class, obtained from Micromonospora purpurea and M. echinospora, that inhibits the growth of both Gram positive and Gram negative bacteria; the sulfate salt is used medicinally. * * *… …   Medical dictionary

  • gentamicin — [ˌdʒɛntə mʌɪsɪn] noun a broad spectrum antibiotic used chiefly for severe systemic infections. Origin 1960s: from genta (of unknown origin) + micin (alt. of mycin) …   English new terms dictionary


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.