gene chip


gene chip
An array of oligonucleotides immobilized on a surface that can be used to screen an RNA sample (after reverse transcription) and thus a method for rapidly determining which genes are being expressed in the cell or tissue from which the RNA came. There are two alternatives for the immobilized oligonucleotides: either a random set of defined sequences or known probes for genes (probes for cytokines, adhesion molecules etc.). In both cases the position on the chip defines the sequence that hybridizes.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • gene chip — noun a microchip that holds DNA probes that form half of the DNA double helix and can recognize DNA from samples being tested • Syn: ↑DNA chip • Hypernyms: ↑chip, ↑microchip, ↑micro chip, ↑silicon chip, ↑microprocessor chip …   Useful english dictionary

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