Protein (400 kD) from skeletal muscle that is missing in Duchenne muscular dystrophy. Its exact role is not yet clear, though it seems to be associated with the cytoplasmic face of the sarcolemma and T-tubules and may form part of the membrane cytoskeleton. There are sequence homologies with non-muscle a-actinin and with spectrin.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Dystrophin — is a rod shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. This complex is variously known as the costamere or the …   Wikipedia

  • Dystrophin — Masse/Länge Primärstruktur 3685 Aminosäuren …   Deutsch Wikipedia

  • dystrophin — dystrophin. См. дистрофин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • dystrophin — A protein found in the sarcolemma of normal muscle; it is missing in individuals with pseudohypertrophic muscular dystrophy and in other forms of muscular dystrophy; its role may be in the linkage of the …   Medical dictionary

  • dystrophin — noun Etymology: dystrophy + 1 in Date: 1987 a protein that is associated with a transmembrane complex of skeletal muscle cells and that is absent in Duchenne muscular dystrophy and deficient or defective in Becker muscular dystrophy …   New Collegiate Dictionary

  • dystrophin — noun A cytoplasmic structural protein that is deficient in some forms of muscular dystrophy …   Wiktionary

  • dystrophin — [dɪs trəʊfɪn] noun Biochemistry a protein found in skeletal muscle, which is absent in sufferers from muscular dystrophy …   English new terms dictionary

  • dystrophin — dys·tro·phin …   English syllables

  • dystrophin — /dɪsˈtroʊfən/ (say dis trohfuhn) noun a cytoplasmic protein important in the maintenance of muscular structure …   Australian English dictionary

  • dystrophin — ˈdistrəˌfin noun ( s) Etymology: dystrophy + in : a protein of high molecular weight that is associated with a transmembrane glycoprotein complex of skeletal muscle cells and is absent in Duchenne muscular dystrophy and deficient or of abnormal… …   Useful english dictionary

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