- diphtheria toxin
An AB exotoxin (62 kD) coded by b corynephage of virulent Corynebacterium diphtheriae strains (that can produce a repressor of toxin production). The B subunit binds to receptors on the surface of the target cell and facilitates the entry of the enzymically active A subunit (21 kD) that ADP-ribosylates elongation factor 2, thereby halting mRNA translation.
Dictionary of molecular biology. 2004.
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