- dermatan sulphate
Glycosaminoglycan (15-40 kD) typical of extracellular matrix of skin, blood vessels and heart. Repeating units of D-glucuronic acid-N-acetyl-D-galactosamine or L-iduronic acid-N-acetyl-D-galactosamine with 1-2 sulphates per unit. Broken down by L-iduronidase, but accumulates intra-lysosomally in Hurler\'s disease and Hunter syndrome.
Dictionary of molecular biology. 2004.
Look at other dictionaries:
Biglycan — is a small leucine rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. CompositionIt consists of a protein core containing leucine rich repeat regions and two… … Wikipedia
Decorin — PDB rendering based on 1xcd … Wikipedia
Chondroitin-glucuronate 5-epimerase — Identifiers EC number 188.8.131.52 CAS number 86417 91 6 … Wikipedia
glycosaminoglycans — (= formerly mucopolysaccharides) Polysaccharide side chains of proteoglycans made up of repeating disaccharide units (more than 100) of amino sugars, at least one of which has a negatively charged side group (carboxylate or sulphate). Commonest… … Dictionary of molecular biology
syndecan — An integral membrane proteoglycan (250 300 kD) associated largely with epithelial cells. The core protein of 294 amino acids has an extracellular domain of 235 amino acids and a single transmembrane domain of 25 amino acids. The extracellular… … Dictionary of molecular biology
biglycan — A small proteoglycan, 150 240 kD, of the extracellular matrix. The core protein has a mass of around 42 kD and is very similar to the core protein of decorin and fibromodulin. All three have highly conserved sequences containing 10 internal… … Dictionary of molecular biology
decorin — A small proteoglycan, 90 140 kD, of the extracellular matrix, so called because it decorates collagen fibres. The core protein has a mass of approximately 42 kD and is very similar to the core protein of biglycan and fibromodulin. All three have… … Dictionary of molecular biology
iduronic acid — (= a L iduronic acid) A uronic acid, derived from the sugar idose, and bearing one terminal carboxyl group. With N acetyl galactosamine 4 sulphate, a component of dermatan sulphate. See iduronidase … Dictionary of molecular biology
Condroitín sulfato — Estructura química de una unidad de cadena de condroitín sulfato. Condroitín 4 sulfato: R1 = H; R2 = SO3H; R3 = H. Condroitín 6 sulfato: R1 = SO3H; R2, R3 = H. El condroitín sulfato o sulfato de condroitina es un glucosaminoglucano sulfatado… … Wikipedia Español
Heparan sulfate — (HS) is a linear polysaccharide found in all animal tissues. It occurs as a proteoglycan (PG) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins. [cite book | title=Proteoglycans:… … Wikipedia