defective virus


defective virus
A virus genetically deficient in replication, but that may nevertheless be replicated when it co-infects a host cell in the presence of a wild-type "helper" virus. Most acute transforming retroviruses are defective, since their acquisition of oncogenes seems to be accompanied by deletion of essential viral genetic information.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • defective virus — noun (biology) A virus that is unable to replicate without a helper (qv) • • • Main Entry: ↑defect * * * defective virus, any one of a class of viruses that contain only a small amount of genetic material and can therefore replicate only in the… …   Useful english dictionary

  • defective virus — defective virus. См. дефектный фаг. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • defective virus — A virus that, by itself, is unable to reproduce when infecting its host cell, but that can grow in the presence of another virus. This other virus provides the necessary molecular machinery that the first virus lacks …   Glossary of Biotechnology

  • defective virus — a virus that cannot be completely replicated or cannot form a protein coat; in some cases replication can proceed if missing gene functions are supplied by other (helper) viruses; see helper v …   Medical dictionary

  • Virus — This article is about the biological agent. For other uses, see Virus (disambiguation). For a generally accessible and less technical introduction to the topic, see Introduction to viruses. Viruses …   Wikipedia

  • Defective interfering particle — Defective interfering particles (DIPs) are virus particles that are missing part or all of their genome. Because of these deletions in their genome, DIPs cannot sustain an infection by themselves. Instead, they depend on co infection with a… …   Wikipedia

  • virus — viruslike, adj. /vuy reuhs/, n., pl. viruses. 1. an ultramicroscopic (20 to 300 nm in diameter), metabolically inert, infectious agent that replicates only within the cells of living hosts, mainly bacteria, plants, and animals: composed of an RNA …   Universalium

  • Virus — A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with… …   Medical dictionary

  • Friend spleen focus-forming virus — Defective virus found in certain strains of Friend helper virus, detected by its ability to form foci in spleens of mice, and believed to be responsible in those strains for the production of a leukaemia associated with polycythemia rather than… …   Dictionary of molecular biology

  • helper virus — a virus (e.g., the Rous associated virus) that aids the development of a defective virus by supplying or restoring the activity of a viral gene or enabling a defective virus (e.g., the Rous sarcoma virus) to form a protein coat …   Medical dictionary


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.