A group of fungal metabolites that inhibit the addition of G-actin to a nucleation site and therefore perturb labile microfilament arrays. Cytochalasin B inhibits at around 1 m g/ml but at about 5 m g/ml begins to inhibit glucose transport. Cytochalasin D affects only the microfilament system and is therefore preferable.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • Citocalasina D — La citocalasina D es un metabolito de origen fúngico capaz, como todas las citocalasinas, de unirse a filamentos de actina y, por ello, impedir su polimerización y elongación. Por ello, repercuten en la morfología celular e inhiben procesos… …   Wikipedia Español

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