(= O-hydroxycinnamic acid)
Pleasant-smelling compound found in many plants and released on wilting (probably a major component of the smell of fresh hay). Has anticoagulant activity by competing with Vitamin K. Coumarin derivatives have anti-inflammatory and antimetastatic properties and inhibit xanthine oxidase and the production of 5-HETE by neutrophils and macrophages. Various derivatives have these activities including esculentin, esculin (6,7-dihydroxycoumarin 6-O-D-glucoside), fraxin, umbelliferone (7-hydroxy coumarin) and scopoletin (6-methoxy-7-hydroxy-coumarin).

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Coumarin — Cou ma*rin (k[=oo] m[.a]*r[i^]n), n. [F., fr. coumarou, a tree of Guiana.] (Chem.) The concrete essence of the tonka bean, the fruit of {Dipterix (formerly Coumarouna) odorata} and consisting essentially of coumarin proper, which is a white… …   The Collaborative International Dictionary of English

  • Coumarin — (Chem.), so v.w. Cumarin …   Pierer's Universal-Lexikon

  • coumarin — [ko͞o′mə rin΄] n. [Fr coumarine < coumarou, tonka bean < Port < Tupí cumaru] a toxic, white crystalline substance, C9H6O2, with the odor of vanilla, obtained from the tonka bean and certain plants or made synthetically: used in perfumes …   English World dictionary

  • Coumarin — Not to be confused with coumadin or dicoumarol. This article is about the sweet smelling plant substance called coumarin. For the anticoagulant rodenticide poisons often called coumarins or coumadins , see 4 hydroxycoumarins. Coumarin …   Wikipedia

  • Coumarin — Strukturformel Allgemeines Name Cumarin Andere Namen 1,2 Benzopyron 2H 1 Benzopyran 2 on o Cumarsäurelacton Ton …   Deutsch Wikipedia

  • coumarin — /kooh meuh rin/, n. a fragrant crystalline substance, C9H6O2, obtained from the tonka bean, sweet clover, and certain other plants or prepared synthetically, used chiefly in soaps and perfumery. Also, cumarin. [1820 30; < F coumarine, equiv. to… …   Universalium

  • coumarin — 1. A general descriptive term applied to anticoagulants and other drugs derived from dicumarol, a component of the Tonka bean. 2. A fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and made synthetically from salicylic… …   Medical dictionary

  • coumarin — kumarinas statusas T sritis chemija formulė OC₉H₆(=O) atitikmenys: angl. coumarin rus. кумарин ryšiai: sinonimas – 1 benzpiran 2 onas …   Chemijos terminų aiškinamasis žodynas

  • coumarin — noun Etymology: French coumarine, from coumarou tonka bean tree, from Spanish or Portuguese; Spanish cumarú, from Portuguese, from Tupi *kumarú, *kumbarú Date: 1830 a toxic white crystalline lactone C9H6O2 with an odor of new mown hay found in… …   New Collegiate Dictionary

  • coumarin — noun the bicyclic aromatic compound 1,2 benzopyrone or any of its derivatives …   Wiktionary

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