COS cells


COS cells
Simian fibroblasts (CV-1 cells) transformed by SV40 that is deficient in the origin of replication region. Express large T-antigen constitutively and if transfected with a vector containing a normal SV40 origin have all the other early viral genes necessary to generate multiple copies of the vector and thus to give very high levels of expression.

Dictionary of molecular biology. 2004.

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