A p80/85 protein first identified as a substrate for src kinase. An F actin binding protein that redistributes to membrane ruffles as a result of growth factor-induced Rac1 activation. Has proline-rich and SH3 domains. Overexpression of cortactin increases cell motility and invasiveness.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Cortactin — PDB rendering based on 1x69 …   Wikipedia

  • CTTNBP2 — Cortactin binding protein 2, also known as CTTNBP2, is a human gene.cite web | title = Entrez Gene: CTTNBP2 cortactin binding protein 2| url = Cmd=ShowDetailView TermToSearch=83992| accessdate = ]… …   Wikipedia

  • Lamellipodia — The lamellipodium (pl. Lamellipodia) is a cytoskeletal actin projection on the mobile edge of the cell. It contains a two dimensional actin mesh; the whole structure pulls the cell across a substrate (Alberts, et al, 2002). Within the… …   Wikipedia

  • SHANK2 — SH3 and multiple ankyrin repeat domains 2, also known as SHANK2, is a human gene.cite web | title = Entrez Gene: SHANK2 SH3 and multiple ankyrin repeat domains 2| url = Cmd=ShowDetailView… …   Wikipedia

  • Gelsolin — is an actin binding protein that is a key regulator of actin filament assembly and disassembly. Gelsolin is one of the most potent members of the actin severing gelsolin/villin superfamily, as it severs with nearly 100% efficiency.cite journal… …   Wikipedia

  • CTNND1 — Catenin (cadherin associated protein), delta 1 Rendering based on PDB 3L6X …   Wikipedia

  • FER (gene) — Fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94), also known as FER, is a human gene.cite web | title = Entrez Gene: FER fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)| url =… …   Wikipedia

  • Drebrin-like — PDB rendering based on 1x67 …   Wikipedia

  • ARHGAP8 — Rho GTPase activating protein 8, also known as ARHGAP8, is a human gene.cite web | title = Entrez Gene: ARHGAP8 Rho GTPase activating protein 8| url = Cmd=ShowDetailView TermToSearch=23779|… …   Wikipedia

  • Wiskott-Aldrich syndrome protein — The Wiskott Aldrich Syndrome Protein (WASp) is a 502 amino acid protein that is expressed in cells of the hematopoietic system. In the inactive state, WASp exists in an auto inhibited conformation with sequences near its C terminus binding to a… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.