contact inhibition of locomotion


contact inhibition of locomotion

Dictionary of molecular biology. 2004.

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  • non-reciprocal contact inhibition — Collision behaviour between different cell types in which one cell shows contact inhibition of locomotion, and the other does not. An example is the interaction between sarcoma cells and fibroblasts (the former not being inhibited) …   Dictionary of molecular biology

  • density dependent inhibition of growth — The phenomenon exhibited by most normal (anchorage dependent) animal cells in culture that stop dividing once a critical cell density is reached. The critical density is considerably higher for most cells than the density at which a monolayer is… …   Dictionary of molecular biology

  • monolayering of cells — Tendency of animal tissue cells growing on solid surfaces to cover the surface with a complete layer only one cell thick, before growing on top of each other. This non random distribution is generated by contact inhibition of locomotion, a… …   Dictionary of molecular biology

  • overlap index — A measure of the extent to which a population of cells in culture forms multilayers. The predicted amount of overlapping is calculated knowing the cell density, the projected area of the nucleus (usually), and assuming a Poisson distribution. The …   Dictionary of molecular biology

  • S180 — (= sarcoma 180) Highly malignant mouse sarcoma cells, often passaged in ascites form. Used in some of the classical studies on contact inhibition of locomotion …   Dictionary of molecular biology

  • nervous system, human — ▪ anatomy Introduction       system that conducts stimuli from sensory receptors to the brain and spinal cord and that conducts impulses back to other parts of the body. As with other higher vertebrates, the human nervous system has two main… …   Universalium

  • avoidance behaviour — Type of activity, exhibited by animals exposed to adverse stimuli, in which the tendency to flee or to act defensively is stronger than the tendency to attack. Vision is the sense that most often produces avoidance behaviour (e.g., small birds… …   Universalium

  • muscle — muscleless, adj. muscly, adj. /mus euhl/, n., v., muscled, muscling, adj. n. 1. a tissue composed of cells or fibers, the contraction of which produces movement in the body. 2. an organ, composed of muscle tissue, that contracts to produce a… …   Universalium

  • mechanoreception — See mechanoreceptor. * * * Ability to detect and respond to mechanical stimuli in one s environment. A slight deformation of a mechanoreceptive neuron causes an electric charge at its surface, activating a response. Mechanoreceptors in pain spots …   Universalium

  • nervous system — Anat., Zool. 1. the system of nerves and nerve centers in an animal or human, including the brain, spinal cord, nerves, and ganglia. 2. a particular part of this system. Cf. autonomic nervous system, central nervous system, peripheral nervous… …   Universalium


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