Chemokine receptors are G-protein-linked serpentine receptors that, in addition to binding chemokines, are used as co-receptors for the binding of immunodeficiency viruses (HIV, SIV, FIV) to leucocytes. CXCR4 is a co-receptor for T-tropic viruses, CCR5 for macrophage-tropic (M-tropic) viruses. Individuals deficient in particular CCRs seem to be resistant to HIV-1 infection.
Dictionary of molecular biology. 2004.
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CXC chemokine receptors — CXCR1 Identifiers Symbol IL8RA Entrez 3577 OMIM … Wikipedia
CC chemokine receptors — protein Name = CCR1 caption = width = HGNCid =1602 Symbol = CCR1 AltSymbols = EntrezGene = 1230 OMIM = 601159 RefSeq = NM 001295 UniProt = P32246 PDB = ECnumber = Chromosome = 3 Arm = p21 Band = LocusSupplementaryData = protein Name = CCR2… … Wikipedia
Chemokine receptor — Typical structure of a chemokine receptor, with seven transmembrane domains and a characteristic DRY motif in the second intracellular domain. Chemokine receptors are usually linked to a G protein through which they signal. Chemokine receptors… … Wikipedia
Chemokine — Small cytokines (intecrine/chemokine), interleukin 8 like Solution structure of interleukin 8, a chemokine of the CXC subfamily Identifiers Symbol IL8 … Wikipedia
Chemokine receptor — A molecule that receives a chemokine and a chemokine dock. A chemokine is a protein that acts as a lure. Chemokines are involved in inflammation, cancer, and infectious diseases. Several chemokine receptors are essential coreceptors for HIV … Medical dictionary
Chemokine — One of a large group of proteins that act as lures and were first found attracting white blood cells. The chemokines are involved in a wide variety of processes including acute and chronic types of inflammation, infectious diseases, and cancer.… … Medical dictionary
chemokine — ˌ noun ( s) Etymology: chem + kine (as in cytokine herein) : any of a group of chemotactic cytokines that are produced by various cells (as at sites of inflammation), that are thought to provide directional cues for the movement of white blood… … Useful english dictionary
C-C chemokine receptor type 7 — Chemokine (C C motif) receptor 7 Identifiers Symbols CCR7; BLR2; CD197; CDw197; CMKBR7; EBI1 External IDs … Wikipedia
C-C chemokine receptor type 6 — Chemokine receptor 6 (gene name CCR6) is a human CC chemokine receptor.CCR6 has also recently been designated CD196 (cluster of differentiation 196). PBB Summary section title = summary text = This protein belongs to family A of G protein coupled … Wikipedia
Rhodopsin-like receptors — Pfam box Symbol = 7tm 1 Name = Rhodopsin like receptors width = caption = Pfam= PF00001 InterPro= IPR000276 SMART= PROSITE = PDOC00211 SCOP = 1f88 TCDB = OPM family= 6 OPM protein= 1gzm PDB=Rhodopsin like receptors are the largest group of G… … Wikipedia