DYNC1H1


DYNC1H1
Dynein, cytoplasmic 1, heavy chain 1

Rendering based on PDB 2BOR.
Identifiers
Symbols DYNC1H1; DHC1; DHC1a; DKFZp686P2245; DNCH1; DNCL; DNECL; DYHC; Dnchc1; HL-3; KIAA0325; p22
External IDs OMIM600112 MGI103147 HomoloGene1053 GeneCards: DYNC1H1 Gene
RNA expression pattern
PBB GE DYNC1H1 211928 at tn.png
PBB GE DYNC1H1 gnf1h10152 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1778 13424
Ensembl ENSG00000197102 ENSMUSG00000018707
UniProt Q14204 O08821
RefSeq (mRNA) NM_001376 NM_030238.2
RefSeq (protein) NP_001367 NP_084514.2
Location (UCSC) Chr 14:
102.43 – 102.52 Mb
Chr 12:
111.84 – 111.91 Mb
PubMed search [1] [2]

Cytoplasmic dynein 1 heavy chain 1 is a protein that in humans is encoded by the DYNC1H1 gene.[1][2][3]


Interactions

DYNC1H1 has been shown to interact with PAFAH1B1[4] and CDC5L.[5]

References

  1. ^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2171247. 
  2. ^ Vaisberg EA, Grissom PM, McIntosh JR (Aug 1996). "Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles". J Cell Biol 133 (4): 831–42. doi:10.1083/jcb.133.4.831. PMC 2120833. PMID 8666668. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2120833. 
  3. ^ "Entrez Gene: DYNC1H1 dynein, cytoplasmic 1, heavy chain 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1778. 
  4. ^ Tai, Chin-Yin; Dujardin Denis L, Faulkner Nicole E, Vallee Richard B (Mar. 2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". J. Cell Biol. (United States) 156 (6): 959–68. doi:10.1083/jcb.200109046. ISSN 0021-9525. PMC 2173479. PMID 11889140. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2173479. 
  5. ^ Ajuh, P; Kuster B, Panov K, Zomerdijk J C, Mann M, Lamond A I (Dec. 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. (ENGLAND) 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=305846. 

Further reading


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