S-ribosylhomocysteine lyase


S-ribosylhomocysteine lyase

In enzymology, a S-ribosylhomocysteine lyase (EC number|4.4.1.21) is an enzyme that catalyzes the chemical reaction

:S-(5-deoxy-D-ribos-5-yl)-L-homocysteine ightleftharpoons L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione

Hence, this enzyme has one substrate, S-(5-deoxy-D-ribos-5-yl)-L-homocysteine, and two products, L-homocysteine and (4S)-4,5-dihydroxypentan-2,3-dione.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is S-(5-deoxy-D-ribos-5-yl)-L-homocysteine L-homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming] . Other names in common use include S-ribosylhomocysteinase, and LuxS. This enzyme participates in methionine metabolism.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1JQW, PDB link|2FQO, and PDB link|2FQT.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37288-63-4."

Gene Ontology (GO) codes


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Look at other dictionaries:

  • List of EC numbers (EC 4) — This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 4.1: Carbon Carbon LyasesEC… …   Wikipedia


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