- Absolute neutrophil count
Absolute neutrophil count (ANC) is a measure of the number of
neutrophil granulocytes(also known as polymorphonuclear cells, PMN's, polys, granulocytes, segmented neutrophils or segs) present in the blood. Neutrophils are a type of white blood cellthat fights against infection.
The ANC is calculated from measurements of the total number of white blood cells (WBC), usually based on the combined percentage of mature neutrophils (sometimes called "segs," or segmented cells) and bands, which are immature neutrophils.
A normal ANC is above 1,500 cells per microliter. An ANC less than 500 cells/µL is defined as neutropenia and significantly increases the risk of infection.
Neutropeniais the condition of a low ANC, and the most common condition where an ANC would be measured is in the setting of chemotherapy for cancer. Neutropeniaincreases the risk of infection.
The unit of ANC is cells per
microlitre( cubic millimetre) of blood.
Source: NCI CTC Toxicity scale Version 2.0 [http://ctep.cancer.gov/forms/CTCv20_4-30-992.pdf]
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