Richard D. Leapman


Richard D. Leapman

Richard D. Leapman, Ph. D (born on Dec. 6th, 1950) is an English physicist, and current scientific director of National Institute of Biomedical Imaging and Bioengineering (NIBIB), since October 2006 [http://www.nih.gov/news/pr/oct2006/nibib-17.htm] NIH news] and a chief of the [http://www.nibib.nih.gov/Research/Intramural/LBPS/SSF#staff laboratory] of bioengineering and physical science. Dr. Leapman's research interests are in the development and application of quantitative [electron microscopy] and the application of novel nanoscale imaging methods to solve problems in structural and cellular biology.

Dr. Leapman has been particularly active in developing the techniques of electron energy loss spectroscopy (EELS) and scanning transmission electron microscopy (STEM) to provide an unprecedented high spatial resolution for nanoanalysis of biological structures. Dr. Leapman has devised new methods for quantifying both elemental and chemical information obtained from inelastic electron scattering, a research area in which he has over one hundred publications [http://www.nibib.nih.gov/Research/Intramural/lbps/publicationspage2#ssfr] Selected publications ] . Recently, Dr. Leapman has extended the techniques of energy filtered transmission electron microscopy (EFTEM) and STEM and combined them with a known technique of tomography to obtain three-dimensional structural and compositional information of cellular components.

Dr. Leapman obtained his Ph.D. in physics from the University of Cambridge, England. He serves on the editorial boards of [http://www.blackwellpublishing.com/journal.asp?ref=0022-2720&site=1 "the journal of microscopy"] and "nanotechnology" and on peer review panels.

References

Chen KG, Valencia JC, Lai B, Zhang G, Paterson JK, Rouzaud F, Berens W, Wincovitch SM, Garfield SH, Leapman RD, Hearing VJ, Gottesman MM. Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9903-7.

Petkova AT, Leapman RD, Guo Z, Yau WM, Mattson MP, Tycko R. Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science. 2005 Jan 14;307(5707):262-5.

Leapman RD, Kocsis E, Zhang G, Talbot TL, Laquerriere P. Three-dimensional distributions of elements in biological samples by energy-filtered electron tomography. Ultramicroscopy. 2004 Jul;100(1-2):115-25

Leapman RD, Gallant PE, Reese TS, Andrews SB. Phosphorylation and subunit organization of axonal neurofilaments determined by scanning transmission electron microscopy. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7820-4.

ee also

* National Institute of Biomedical Imaging and Bioengineering
*National Institutes of Health

External links

* [http://www.nih.gov NIH homepage]
** [http://www.nih.gov/icd/ NIH Institutes, Centers and Offices]
** [http://health.nih.gov/ NIH Health Information]
** [http://history.nih.gov/exhibits/history/index.html History of NIH]
* [http://www.nih.gov/news/radio/nihpodcast.htm NIH Podcast]


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Richard Ingrams — (born August 19, 1937) was a co founder and second editor of the British satirical magazine Private Eye , taking over from Christopher Booker in 1963. He now edits The Oldie magazine.CareerIngrams parents were Leonard St Clair Ingrams and… …   Wikipedia

  • Deinococcus radiodurans — A tetrad of D. radiodurans Scientific classification Kingdom: Bacteria …   Wikipedia

  • National Institute of Biomedical Imaging and Bioengineering — The National Institute of Biomedical Imaging and Bioengineering (NIBIB) is the newest of the National Institutes of Health (NIH) research institutes and centers and was formed in the United States when President Bill Clinton signed it into law on …   Wikipedia

  • Прополка Ковент-Гардена, или мировой судья из Миддлсекса — The Weeding of the Covent Garden, or the Middlesex Justice of Peace (альтернативное название The Covent Garden Weeded) …   Википедия

  • The Weeding of Covent Garden — The Weeding of the Covent Garden, or the Middlesex Justice of Peace, alternatively titled The Covent Garden Weeded, [Modern usage often drops the definitive article before Covent Garden. ] is a Caroline era stage play, a comedy written by Richard …   Wikipedia

  • Salmacida Spolia — was the last masque performed at the English Court before the outbreak of the English Civil War. Written by Sir William Davenant, with costumes, sets, and stage effects designed by Inigo Jones and with music by Lewis Richard, it was performed at… …   Wikipedia

  • Chiswick House — Chiswick House …   Wikipedia

  • Мердок, Руперт — Американский медиамагнат, глава News Corporation Американский предприниматель австралийского происхождения, создатель и глава медиагиганта News Corporation, его генеральный директор (с 1979 года) и председатель совета директоров (с 1991 года).… …   Энциклопедия ньюсмейкеров

  • David Cameron — This article is about the British prime minister. For other uses, see David Cameron (disambiguation). The Right Honourable David Cameron MP …   Wikipedia

  • Nigel Dempster — Nigel Richard Patton Dempster (1 November 1941 in Calcutta, India 12 July 2007 in Ham, Surrey) was a British journalist, author, broadcaster and diarist. Best known for his celebrity gossip columns in newspapers, his work appeared in the Daily… …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.