Adipocyte


Adipocyte

Adipocytes are the cells that primarily compose adipose tissue, specialized in storing energy as fat.

There are two types of adipose tissue, white adipose tissue (WAT) and brown adipose tissue (BAT), which are also known as white fat and brown fat, respectively, and comprise two types of fat cells.

White fat cells (unilocular cells)

White fat cells contain a large lipid droplet surrounded by a ring of cytoplasm. The nucleus is flattened and located on the periphery. A typical fat cell is 0.1mm in diameter with some being twice that size and others half that size. The fat stored is in a semi-liquid state, and is composed primarily of triglycerides and cholesteryl ester. White fat cells secrete resistin, adiponectin, and leptin. An average adult has 30 billion fat cells with a weight of 30 lbs or 13.5 kg. If excess weight is gained as an adult fat cells increase in size about fourfold before dividing and increasing the absolute number of fat cells present. [cite book |author=Pool, Robert |title=Fat: fighting the obesity epidemic |publisher=Oxford University Press |location=Oxford [Oxfordshire] |year=2001 |pages= |isbn=0-19-511853-7]

Brown fat cells (multilocular cells)

Brown fat cells are polygonal in shape. Unlike white fat cells, these cells have considerable cytoplasm, with lipid droplets scattered throughout. The nucleus is round, and, although eccentrically located, it is not in the periphery of the cell. The brown color comes from the large quantity of mitochondria. Brown fat, also known as "baby fat," is used to generate heat.

Lineage

Although the lineage of adipocytes is still unclear, "preadipocytes" are undifferentiated fibroblasts that can be stimulated to form adipocytes.

Mesenchymal stem cells can differentiate into adipocytes, connective tissue, muscle or bone.

Areolar connective tissue is composed of adipocytes.

References

External links

* - "Connective Tissue: unilocular (white) adipocytes "
* - "Connective Tissue: multilocular (brown) adipocytes"


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Look at other dictionaries:

  • adipocyte — [ adipɔsit ] n. m. • 1970; de adipo et cyte ♦ Biol. Cellule spécialisée dans le stockage des lipides. ● adipocyte nom masculin Cellule de l organisme contenant des lipides. adipocyte [adipɔsit] n. m. ÉTYM. D. i.; de …   Encyclopédie Universelle

  • adipocyte — adipocyte. См. адипоцит. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Adipocyte — Les adipocytes sont des cellules présentes dans les tissus adipeux, spécialisées dans le stockage de la graisse. Les adipocytes constituent donc une partie de nos réserves d énergie. Ils stockent les lipides jusqu’à une taille cellulaire critique …   Wikipédia en Français

  • Adipocyte — A fat cell, a connective tissue cell that has differentiated and become specialized in the synthesis (manufacture) and storage of fat. The adipocyte is important to the body in maintaining proper energy balance, storing calories in the form of… …   Medical dictionary

  • adipocyte — noun Date: 1959 fat cell …   New Collegiate Dictionary

  • adipocyte — a fat cell …   Dictionary of ichthyology

  • adipocyte — Mesenchymal cell in fat tissue that has large lipid filled vesicles. There may be distinct types in white and brown fat. 3T3 L1 cells are often used as a model system; they can be induced to differentiate with dexamethasone/insulin/IBMX treatment …   Dictionary of molecular biology

  • adipocyte — /ad euh poh suyt /, n. See fat cell. [ADIPO + CYTE] * * * …   Universalium

  • adipocyte — noun a type of cell, present in adipose tissue, where fat is stored as a source of energy …   Wiktionary

  • adipocyte — [ adɪpə(ʊ)sʌɪt] noun Biology a cell specialized for the storage of fat, found in connective tissue. Origin 1930s: from adipose + cyte …   English new terms dictionary


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